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Netrin receptor unc-5

Summary

UniProt ID: Q26261
Gene Symbol: unc-5 B0273.4
Gene ID: 177334
Organism: Caenorhabditis elegans

External Links

GlycoProtDB: GPDB0000823
Re-Glyco: Q26261

Annotation

Keyword: 3D-structure Alternative splicing Cell membrane Cell projection Developmental protein Disulfide bond Glycoprotein Immunoglobulin domain Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	Reference
ventral cord development	IMP	PMID
ventral cord development	IGI	PMID
motor neuron axon guidance	IMP	PMID PMID PMID PMID PMID
motor neuron axon guidance	IGI	PMID PMID
motor neuron axon guidance	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

establishment or maintenance of cell polarity [inference]

establishment or maintenance of cytoskeleton polarity [inference]

establishment or maintenance of actin cytoskeleton polarity

signal transduction [inference]

cell surface receptor signaling pathway [inference]

netrin-activated signaling pathway

actin filament-based process [inference]

actin cytoskeleton organization [inference]

establishment or maintenance of actin cytoskeleton polarity

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesodermal cell migration

distal tip cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

establishment or maintenance of actin cytoskeleton polarity

establishment or maintenance of cytoskeleton polarity [inference]

establishment or maintenance of actin cytoskeleton polarity

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

reproductive process [inference]

developmental process involved in reproduction [inference]

gonad morphogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

gonad morphogenesis

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

gonad morphogenesis

male anatomical structure morphogenesis [inference]

nematode male tail tip morphogenesis

anatomical structure development [inference]

animal organ development [inference]

ventral cord development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

negative chemotaxis [inference]

chemorepulsion of axon

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

positive regulation of axon extension

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

regulation of developmental growth [inference]

regulation of axon extension [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

regulation of locomotion [inference]

positive regulation of locomotion

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of dorsal/ventral axon guidance

positive regulation of biological process [inference]

positive regulation of locomotion

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of anterior/posterior axon guidance

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of dorsal/ventral axon guidance

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of developmental growth [inference]

regulation of axon extension [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

netrin-activated signaling pathway

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of anterior/posterior axon guidance

positive regulation of axonogenesis [inference]

positive regulation of axon extension

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

positive regulation of axon extension

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of anterior/posterior axon guidance

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of axonogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of dorsal/ventral axon guidance

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of cytoskeleton organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of anterior/posterior axon guidance

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of supramolecular fiber organization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	IC	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
axonal growth cone	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

membrane microdomain [inference]

membrane raft

site of polarized growth [inference]

growth cone [inference]

axonal growth cone

Displaying **all 4** entries
GO Term	Evidence Code	Reference
netrin receptor activity	ISS	GO_REF
netrin receptor activity	IMP	PMID
netrin receptor activity	IBA	GO_REF
netrin receptor activity	IEA	GO_REF

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

netrin receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MEDDTPDVSSDSNGDAAYSDYFLDYKSIMDEITITTQPKSGYVIRNKPLRLQCRANHATKIRYKCSSKWIDDSRIEKLIGTDSTSGVGYIDASVDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATNVANSRKTDPVEVQIYVDGGWSEWSPWIGTCHVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEEEMTRSCKVPCKLDGGWSSWSDWSACSSSCHRYRTRACTVPPPMNGGQPCFGDDLMTQECPAQLCTADSSRIVISDTAVYGSVASIFIVASFILAILAMFCCKRGNSKKSKPLKPQKMNSEKAGGIYYSEPPGVRRLLLEHQHGTLLGEKISSCSQYFEPPPLPHSTTLRSGKSAFSGYSSTRNAGSRAALIQECSSSSSGSGGKRTMLRTSSSNCSDDDNYATLYDYMEDKSVLGLDTSQNIVAAQIDSNGARLSLSKSGARLIVPELAVEGEKMLYLAVSDTLTDQPHLKPIESALSPVIVIGQCDVSMSAHDNILRRPVVVSFRHCASTFPRDNWQFTLYADEGSGWQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVFGPTEMSAYRRPFELRVYCVPETGAAMESVWKQEDGSRLLCESNDFILNEKGNLCICIEDVIPGFSCDGPEVVEISETQHRFVAQNGLHCSLKFRPKEINGSQFSTRVIVYQKASSTEPMVMEVSNEPELYDATSEEREKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLERFLSAFPQIVSP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	Source
178			GlycoProtDB
206	N-linked (GlcNAc...) asparagine	17761667	UniProt
305	C-linked (Man) tryptophan	23562325	UniProt
308	C-linked (Man) tryptophan	23562325	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Netrin-1 signaling	Caenorhabditis elegans

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements