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Kit ligand

Summary

UniProt ID: Q28132
Gene Symbol: KITLG SCF
Gene ID: 281885
Organism: Bos taurus (domestic cattle)

External Links

PubChem: Q28132
Re-Glyco: Q28132

Annotation

Keyword: Alternative splicing Cell adhesion Cell membrane Cell projection Cytoskeleton Disulfide bond Glycoprotein Growth factor Pyrrolidone carboxylic acid Reference proteome Secreted Signal Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
developmental process involved in reproduction
cell adhesion	IEA	GO_REF
positive regulation of cell population proliferation	IBA	GO_REF
positive regulation of biosynthetic process
animal organ development

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

reproductive process [inference]

developmental process involved in reproduction

developmental process [inference]

developmental process involved in reproduction

anatomical structure development [inference]

animal organ development

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
extracellular region	IEA	GO_REF
cytoplasm	ISS	GO_REF
cytoplasm	IEA	GO_REF
cytoskeleton	IEA	GO_REF
plasma membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

actin-based cell projection [inference]

filopodium

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

Displaying **all 3** entries
GO Term	Evidence Code	Reference
cytokine activity
stem cell factor receptor binding	IEA	GO_REF
growth factor activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

stem cell factor receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKKTQTWIITCIYLQLLLFNPLVHTQGICSNRVTDDVKDVTKLVANLPKDYMITLKYVPGMDVLPSHCWISEMVEQLSVSLTDLLDKFSNISEGLSNYCIIDKLVKIVDDLVECMEEHSSENVKKSSKSPEPRQFTPEKFFGIFNKSIDAFKDLEIVASKMSECVISSTSSPEKDSRVSVTKPFMLPPVAASSLRNDSSSSNRKASNSIEDSSLQWAAVALPAFFSLVIGFAFGAFYWKKKQPNLTRTVENRQINEEDNEISMLQEKEREFQEV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
90	N-linked (GlcNAc...) asparagine	UniProt
145	N-linked (GlcNAc...) asparagine	UniProt
196	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
PI3K/AKT Signaling	Bos taurus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Bos taurus
RAF/MAP kinase cascade	Bos taurus
Regulation of KIT signaling	Bos taurus
Signaling by SCF-KIT	Bos taurus
Transcriptional and post-translational regulation of MITF-M expression and activity	Bos taurus

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