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Fibroblast growth factor receptor

Summary

UniProt ID: Q28J96
Gene Symbol: TNeu076b03.1-001 X1FGFR XFGFR-1 bfgfr cd331 cek fgfbr fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 hbgfr kal2 n-sam ogd xfgfr1
Gene ID: 548648
Organism: Xenopus tropicalis (tropical clawed frog)

External Links

Re-Glyco: Q28J96

Annotation

Keyword: ATP-binding Cell membrane Cytoplasm Cytoplasmic vesicle Disulfide bond Glycoprotein Immunoglobulin domain Nucleus Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase Ubl conjugation

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
positive regulation of cell population proliferation	IEA	GO_REF
positive regulation of macromolecule metabolic process
cell differentiation	IEA	GO_REF
animal organ development	IEA	GO_REF
regulation of primary metabolic process

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation

developmental process [inference]

anatomical structure development [inference]

animal organ development

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process

regulation of cellular process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process

regulation of primary metabolic process

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process

Displaying **all 4** entries
GO Term	Evidence Code	Reference
nucleus	IEA	GO_REF
cytosol	IEA	GO_REF
plasma membrane	IEA	GO_REF
cytoplasmic vesicle	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying **all 2** entries
GO Term	Evidence Code	Reference
fibroblast growth factor receptor activity	IEA	GO_REF
ATP binding	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MFSGRSLLLWGVLLGAALSVARPPSTLPDQVAPKTKTDVEPYSARPGDRITLQCRLREDVQSINWAKNEMQLSETNRTRITGEEIQISNAGPEDNGVYTCVTNGPSGTYTVLFSVNVSDALPSAEDDDDDDDNSSSEEKASENSKPNRPFWSHPEKMEKKLHAVPAAKTVKFRCPANGTPQPNLRWLKNGKEFRQDQRIGGYKVRSQTWSLIMDSVVPSDKGNYTCIVENKYGTLNHTYQLDVVERSPHRPILQAGLPANTSVIVGSTAEFFCKVYSDPQPHIQWLRHIEINGSRVASDGFPYVEILKTAGVNTSDKDMEVLHLRNVTFEDAGQYTCLAANSIGISHHSAWLTVLEVEDDKPAPLASPLQLEIIIYCTGAAFVSAMVITIIIFKMKHPSKKSDFNSQLAVHKLAKSIPLRRQVTVSGDSNSSMHSGVILVRPSRLSSSGTPMLSGVSEYELPEDPRWEVARDRLILGKPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPTCAPDQLLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGHRMDKPTTCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRILALSSNQEYLDLSMPVNQYSPCFPDTRSSTCSSGEDSVFSHDPLPDEPCLPKYSNGGLKKR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
76	N-linked (GlcNAc...) asparagine	UniProt
116	N-linked (GlcNAc...) asparagine	UniProt
223	N-linked (GlcNAc...) asparagine	UniProt
236	N-linked (GlcNAc...) asparagine	UniProt
260	N-linked (GlcNAc...) asparagine	UniProt
292	N-linked (GlcNAc...) asparagine	UniProt
313	N-linked (GlcNAc...) asparagine	UniProt
326	N-linked (GlcNAc...) asparagine	UniProt