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Hepatic triacylglycerol lipase

Summary

UniProt ID

Q3SZ79

Gene Symbol

LIPC

Gene ID

[535192]

Organism

Bos taurus (domestic cattle)

External Links

PubChem: Q3SZ79
Re-Glyco: Q3SZ79

Annotation

Keyword: Glycoprotein HDL Heparin-binding Hydrolase Lipid degradation Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
fatty acid biosynthetic process	IBA	GO_REF
fatty acid biosynthetic process	IEA	GO_REF
cholesterol metabolic process
triglyceride catabolic process	IBA	GO_REF
triglyceride catabolic process	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

lipid catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride catabolic process

acylglycerol catabolic process [inference]

triglyceride catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process

lipid catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride catabolic process

acylglycerol catabolic process [inference]

triglyceride catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

very-low-density lipoprotein particle remodeling

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

very-low-density lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

very-low-density lipoprotein particle remodeling

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

very-low-density lipoprotein particle remodeling

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

acylglycerol homeostasis [inference]

triglyceride homeostasis

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

sterol transport [inference]

cholesterol transport

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport

Displaying **all 2** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
high-density lipoprotein particle

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

extracellular protein-containing complex [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
lipoprotein lipase activity	IBA	GO_REF
phosphatidylcholine lysophospholipase A1 activity	ISS	GO_REF
phosphatidylcholine lysophospholipase A1 activity	IEA	GO_REF GO_REF
triacylglycerol lipase activity	ISS	GO_REF
triacylglycerol lipase activity	IEA	GO_REF GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

triacylglycerol lipase activity

lipoprotein lipase activity

phospholipase activity [inference]

glycerophospholipase activity [inference]

A1-type glycerophospholipase activity [inference]

glycerophospholipid phospholipase A1 activity

lysophospholipase A1 activity [inference]

phosphatidylcholine lysophospholipase A1 activity

carboxylic ester hydrolase activity [inference]

triacylglycerol lipase activity

lipoprotein lipase activity

A1-type glycerophospholipase activity [inference]

glycerophospholipid phospholipase A1 activity

lysophospholipase A1 activity [inference]

phosphatidylcholine lysophospholipase A1 activity

binding [inference]

protein binding [inference]

apolipoprotein binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MENPLCVSIFLFYCILIQSSAHGQSLGPESFGRRSRAAETNKTPQETRTKFLLFRGETDKGCQILLNHSDTLQQCGFNSSLPLVMIVHGWLVDDILEDWVWEMVAALKSQLAQSVNVGLAEWVTLAHNHYTTAVRNTRLVGQEIAALLQWLQESVQFSPSHVHLIGYSLGAHVSGFAGSYMSRKHKIGRITGLDAAGPLFEKASLSDRLSPDDANFVDAIHTFTWEHMGLSVGMKQPIAHYDFYPNGGSYQPGCHFLELYKHFAKHGLNAITRTVKCAHERSVHLFIDSLLHADMQSMAYLCRDMDRFSQGLCLSCKKGRCNTLGYHTRQERQSKKSKSLFLVTRAQSPFKVYHYQFKIRFINQTENPVEPTFTVSFLGTRGERQKIPITLSKGITSNETYSFLITLDVDIGELIMIKFKWENRMVWSNVWNTVQTIIPWGRGSLHSGLALKSIRVKVGETQQRMTFCSENMNDLLLHPAREKTFVRCEANSETLKRKIR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
67	N-linked (GlcNAc...) asparagine	UniProt
78	N-linked (GlcNAc...) asparagine	UniProt
363	N-linked (GlcNAc...) asparagine	UniProt
398	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Assembly of active LPL and LIPC lipase complexes	Bos taurus
Chylomicron clearance	Bos taurus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements