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Neuropilin

Summary

UniProt ID: Q3U5I8
Gene Symbol: Als2cr19 Nrp2
Gene ID: 18187
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0004597
Re-Glyco: Q3U5I8

Annotation

Keyword: Calcium Developmental protein Differentiation Disulfide bond Glycoprotein Heparin-binding Metal-binding Neurogenesis Receptor Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
angiogenesis	IEA	GO_REF
outflow tract septum morphogenesis	IEA	GO_REF
facial nerve structural organization	IEA	GO_REF
vestibulocochlear nerve structural organization	IEA	GO_REF
gonadotrophin-releasing hormone neuronal migration to the hypothalamus	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

sympathetic neuron projection extension

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration [inference]

trunk neural crest cell migration [inference]

ventral trunk neural crest cell migration

neural crest cell migration involved in autonomic nervous system development

neuron migration [inference]

gonadotrophin-releasing hormone neuronal migration to the hypothalamus

hypothalamus cell migration [inference]

hypothalamic tangential migration using cell-axon interactions [inference]

gonadotrophin-releasing hormone neuronal migration to the hypothalamus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

sensory neuron axon guidance

sympathetic neuron projection guidance

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

ganglion morphogenesis [inference]

dorsal root ganglion morphogenesis

cardiac septum morphogenesis [inference]

outflow tract septum morphogenesis

anatomical structure arrangement [inference]

cranial nerve structural organization [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

tissue development [inference]

ganglion development [inference]

sympathetic ganglion development

cranial ganglion development [inference]

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

sympathetic neuron projection extension

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

sympathetic neuron projection extension

developmental growth involved in morphogenesis [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

sympathetic neuron projection extension

Displaying 1 entry
GO Term	Evidence Code	Reference
membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

Displaying **all 4** entries
GO Term	Evidence Code	Reference
vascular endothelial growth factor receptor activity	IEA	GO_REF
heparin binding
semaphorin receptor activity	IEA	GO_REF GO_REF
metal ion binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

vascular endothelial growth factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

vascular endothelial growth factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

vascular endothelial growth factor receptor activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

semaphorin receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

vascular endothelial growth factor receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDMFPLTWVFLALYFSGHEVRSQQDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSVLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPRMEIILQFLTFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSKLRSSTGILSLTFHTDMAVAKDGFSARYYLIHQEPPENFQCNVPLGMESGRIANEQISASSTFSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQKGYYVKSYKLEVSTNGEDWMVYRHGKNHKIFQANNDATEVVLNKLHMPLLTRFIRIRPQTWHLGIALRLELFGCRVTDAPCSNMLGMLSGLIADTQISASSTREYLWSPSAARLVSSRSGWFPRNPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQTKLFEGNMHYDTPDIRRFDPVPAQYVRVYPERWSPAGIGMRLEVLGCDWTDSKPTVETLGPTVKSEETTTPYPMDEDATECGENCSFEDDKDLQLPSGFNCNFDFPEETCGWVYDHAKWLRSTWISSANPNDRTFPDDKNFLKLQSDGRREGQYGRLISPPVHLPRSPVCMEFQYQAMGGHGVALQVVREASQESKLLWVIREDQGSEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEISIDDIRISTDVPLENCMEPISAFAGGTLPPGTEPTVDTVPVQPIPAYWYYVMAAGGAVLVLASVVLALVLHYHRFRYAAKKTDHSITYKTSHYTNGAPLAVEPTLTIKLEQERGSHC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites