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MIRAGE

Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 1

Summary

UniProt ID: Q3UGD6
Gene Symbol: Slc7a1 Atrc1 Rec-1
Gene ID: 11987
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0004768
Re-Glyco: Q3UGD6

Annotation

Keyword: Amino-acid transport Cell membrane Glycoprotein Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
lysine transport	IEA	GO_REF
ornithine transport	IEA	GO_REF
positive regulation of T cell proliferation
L-histidine import across plasma membrane	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-histidine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

azole transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

L-histidine import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

localization [inference]

establishment of localization [inference]

transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-histidine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

basic amino acid transport [inference]

lysine transport

L-amino acid transport [inference]

L-lysine transport [inference]

lysine transport

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

ornithine transport

organic cation transport [inference]

ornithine transport

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

L-lysine transport [inference]

lysine transport

organic anion transport [inference]

carboxylic acid transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

L-amino acid transport [inference]

L-lysine transport [inference]

lysine transport

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

ornithine transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

L-amino acid transport [inference]

L-lysine transport [inference]

lysine transport

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

ornithine transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-histidine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

azole transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

L-histidine import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

nitrogen compound transport [inference]

aromatic amino acid transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

L-amino acid transport [inference]

L-lysine transport [inference]

lysine transport

L-alpha-amino acid transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

ornithine transport

azole transmembrane transport [inference]

L-histidine transmembrane transport [inference]

L-histidine import across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

L-histidine import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

Displaying **all 3** entries
GO Term	Evidence Code	Reference
basolateral plasma membrane	IEA	GO_REF
apical plasma membrane	IEA	GO_REF
protein-containing complex	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane region [inference]

Displaying **all 3** entries
GO Term	Evidence Code	Reference
L-histidine transmembrane transporter activity	IEA	GO_REF
L-lysine transmembrane transporter activity	IEA	GO_REF GO_REF
L-arginine transmembrane transporter activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

basic amino acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

azole transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGCKNLLGLGQQMLRRKVVDCSREESRLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISFLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCFIVVSGFVKGSIKNWQLTEKNFSCNNNDTNVKYGEGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDIDSPLPGAFKHQGWEEAKYAVAIGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFKFLAKINNRTKTPVIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMARTTEELDRVDQNELVSASESQTGFLPVAEKFSLKSILSPKNVEPSKFSGLIVNISAGLLAALIITVCIVAVLGREALAEGTLWAVFVMTGSVLLCMLVTGIIWRQPESKTKLSFKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWMLIGFTIYFGYGIWHSEEASLAAGQAKTPDSNLDQCK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
223				GlycoProtDB
229				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026