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Peroxidasin homolog [Cleaved into: PXDN active fragment]

Summary

UniProt ID: Q3UQ28
Gene Symbol: Kiaa0230 Pxdn
Gene ID: 69675
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0004884

GlyConnect

Peroxidasin homolog

GlyGen

Q3UQ28

PubChem

Q3UQ28

Re-Glyco

Q3UQ28

Annotation

Keyword: Basement membrane Calcium Disulfide bond Endoplasmic reticulum Glycoprotein Heme Hydrogen peroxide Immunoglobulin domain Leucine-rich repeat Phosphoprotein Reference proteome Repeat Signal

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
angiogenesis	ISS	GO_REF
angiogenesis	ISO	GO_REF
eye development	IMP	PMID
response to oxidative stress	IEA	GO_REF
cell adhesion	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

metabolic process [inference]

catabolic process [inference]

hydrogen peroxide catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein homotrimerization

protein trimerization [inference]

protein homotrimerization

extracellular matrix assembly [inference]

basement membrane assembly

extracellular structure organization [inference]

extracellular matrix organization

collagen fibril organization

basement membrane organization

basement membrane assembly

extracellular matrix assembly [inference]

basement membrane assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein homotrimerization

protein trimerization [inference]

protein homotrimerization

external encapsulating structure organization [inference]

extracellular matrix organization

collagen fibril organization

basement membrane organization

basement membrane assembly

extracellular matrix assembly [inference]

basement membrane assembly

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

animal organ development [inference]

sensory organ development [inference]

eye development

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
basement membrane	IDA	PMID
basement membrane	IEA	GO_REF
obsolete extracellular space
endoplasmic reticulum	ISS	GO_REF
endoplasmic reticulum	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

external encapsulating structure [inference]

extracellular matrix

basement membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

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GO Term	Evidence Code	Reference
peroxidase activity	ISS	GO_REF
peroxidase activity	ISO	GO_REF
peroxidase activity	IBA	GO_REF
peroxidase activity	IEA	GO_REF GO_REF
extracellular matrix structural constituent	RCA	PMID PMID

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on peroxide as acceptor

peroxidase activity

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding [inference]

laminin binding [inference]

laminin-1 binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

tetrapyrrole binding [inference]

heme binding

extracellular matrix binding [inference]

laminin binding [inference]

laminin-1 binding

antioxidant activity [inference]

peroxidase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAVRPTRRCLLALLLCFAWWAMAVVASKQGAGCPSRCLCFRTTVRCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRSLNTLLLNNNQIKKIPNGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPESFQHLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKTYAQSGNAQAAATCEYPRRIQGRSVATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQEADEGVYQCMAKNVAGEAKTQEVTLRYLGSPARPTFVIQPQNTEVLVGESVTLECSATGHPLPQITWTRGDRTPLPIDPRVNITPSGGLYIQNVAQSDSGEYTCFASNSVDSIHATAFIIVQALPQFTVTPQSRVVIEGQTVDFQCAAKGHPQPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDMTVEVGTNVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGTADAGRYECVARNTIGYASVSMVLSVNVPDVSRNGDPYVATSIVEAIATVDRAINSTRTHLFDSRPRSPNDLLALFRYPRDPYTVGQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLSLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKAVYENGFNTPRGINSQRQYNGHVLPMPRLVSTTLIGTEVITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSSVCSNDPPCFSVMIPPNDPRVRSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTDHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHETRKIVGAEIQHITYRHWLPKILGEVGMKMLGEYRGYDPSVNAGIFNAFATAAFRFGHTLINPLLYRLDENFEPIPQGHVPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRIPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIKSPVIREKLQRLYGSTLNIDLFPALMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLWYENPGVFSPAQLTQLKQTSLARILCDNSDNITRVQQDVFRVAEFPHGYSSCEDIPRVDLRVWQDCCEDCRTRGQFNAFSYHFRGRRSLEFSYEDDKPTKRARWRKALSVKHGKHLSNATSATHEHLEGPATNDLKEFVLEMQKIITDLRKQINSLESRLSTTECVDDSGESHGGNTKWKKDPCTVCECKNGQITCFVEACQPAACPQPVKVEGACCPVCLKNTAEEKP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 11 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
387	N-linked (GlcNAc...) asparagine			UniProt GlyGen
389				GlyGen
637	N-linked (GlcNAc...) asparagine			UniProt GlyGen
696	N-linked (GlcNAc...) asparagine			UniProt GlyGen
716	N-linked (GlcNAc...) asparagine			UniProt GlyGen
727				GlycoProtDB
728	N-linked (GlcNAc...) asparagine	30899004	G62765YT G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
961	N-linked (GlcNAc...) asparagine			UniProt GlyGen
1175	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
1277	N-linked (GlcNAc...) asparagine	30899004	G80920RR G39188ZX G06110VR	GlycoProtDB UniProt GlyGen GlyConnect