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Troponin I, cardiac muscle

Summary

UniProt ID: Q497F1
Gene Symbol: Tnni3
Gene ID: 21954
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0005087
Re-Glyco: Q497F1

Annotation

Keyword: Acetylation Actin-binding Coiled coil Muscle protein

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
regulation of smooth muscle contraction	IEA	GO_REF
regulation of cardiac muscle contraction by calcium ion signaling	IEA	GO_REF
ventricular cardiac muscle tissue morphogenesis	IEA	GO_REF
cardiac muscle contraction	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling [inference]

regulation of cardiac muscle contraction by calcium ion signaling

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction [inference]

cardiac muscle contraction

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

cardiac muscle tissue morphogenesis [inference]

ventricular cardiac muscle tissue morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling [inference]

regulation of cardiac muscle contraction by calcium ion signaling

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of smooth muscle contraction

regulation of striated muscle contraction [inference]

regulation of cardiac muscle contraction [inference]

regulation of cardiac muscle contraction by calcium ion signaling

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of cardiac muscle contraction [inference]

regulation of cardiac muscle contraction by calcium ion signaling

Displaying **all 2** entries
GO Term	Evidence Code	Reference
cardiac myofibril	IEA	GO_REF
cardiac Troponin complex	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

troponin complex [inference]

cardiac Troponin complex

cellular anatomical structure [inference]

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

contractile muscle fiber [inference]

myofibril [inference]

cardiac myofibril

intracellular organelle [inference]

intracellular membraneless organelle [inference]

contractile muscle fiber [inference]

myofibril [inference]

cardiac myofibril

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

contractile muscle fiber [inference]

myofibril [inference]

cardiac myofibril

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
calcium channel inhibitor activity	IEA	GO_REF
protein kinase binding	IEA	GO_REF
protein domain specific binding	IEA	GO_REF
troponin C binding	IEA	GO_REF
troponin T binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein-containing complex binding [inference]

actin filament binding

molecular function regulator activity [inference]

molecular function inhibitor activity [inference]

transporter inhibitor activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

calcium channel inhibitor activity

transporter regulator activity [inference]

channel regulator activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

calcium channel inhibitor activity

ion channel regulator activity [inference]

calcium channel regulator activity [inference]

calcium channel inhibitor activity

ion channel inhibitor activity [inference]

calcium channel inhibitor activity

transporter inhibitor activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

calcium channel inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKSKISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLRTRCQPLELDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLDLRAHLKQVKKEDIEKENREVGDWRKNIDALSGMEGRKKKFEG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
122				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110313	hypertrophic cardiomyopathy 7	Alliance of Genome Resources
DOID:397	restrictive cardiomyopathy	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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International Collaboration

Acknowledgements