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Beta-mannosidase

Summary

UniProt ID: Q4FZV0
Gene Symbol: Manba
Gene ID: 310864
Organism: Rattus norvegicus (Norway rat)

External Links

PubChem: Q4FZV0
Re-Glyco: Q4FZV0

Annotation

Keyword: Alternative splicing Disulfide bond Glycoprotein Glycosidase Lysosome Reference proteome Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
carbohydrate metabolic process	IEA	GO_REF
glycoprotein catabolic process	ISS	GO_REF
glycoprotein catabolic process	ISO	GO_REF
glycoprotein catabolic process	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
lysosome	ISS	GO_REF
lysosome	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
beta-mannosidase activity	ISS	GO_REF
beta-mannosidase activity	ISO	GO_REF
beta-mannosidase activity	IDA	PMID
beta-mannosidase activity	IBA	GO_REF
beta-mannosidase activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

mannosidase activity [inference]

beta-mannosidase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

D-mannose binding

small molecule binding [inference]

monosaccharide binding [inference]

D-mannose binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MHLHLLFLLALCGAGCMAAGPSYSLRGSWRVSNGNSSLELPATVPGYVHSALQQHGLIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNRSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTRYSFDVTNVVKDVNSLKLRFQSAVQYAECQSKAHTQYRVPPECPPVEQKGECHVNFIRKEQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDHLTFLPLYDNTSQAWTIEIEASFDVVSTKPVGGQVTIAIPELKTQQANHIELQHGQRIVKLLVKIRKDVTVETWWPHGHGNQTGYNTTILFALDGGLKIEKAAKVYFRTVQLIEEPITGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSELLQLLLQSAVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLESVRKEVTYQVRRLKSHPSVIIWSGNNENEVALRVNWFHVNPRDLGTYINDYVTLYVKTIREIVLSEDRSRPFIASSPTNGVKTMTEGWISKDPYSTQYGDMHFYDYFSDCWDWKVFPKARLVSEYGYQSWPSFSTLQKVSRQEDWSYSSRFSLHRQHHGNGNNEMLHQVQLHFQLPQRRDPVRAFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVNGEGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFAQRFFAPLLPVGFEDEGVFYVYGVSDLHKDYPTKLTVRLHRWSSQKPLCTFVSLSAVIKAGEAMVLFQMPVSKLLKRCKECTRDTCVVSFYLSTDNELFSPTNYHFLSSLKDAKGMVKANITVSISQKGDLFVFDLKSSTSAITPFVWLDVGSIPGRFSDNGFLMIKKELSVLFYPWKPTSKSELQQAFSVTSLTDLY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
35	N-linked (GlcNAc...) asparagine	UniProt
77	N-linked (GlcNAc...) asparagine	UniProt
89	N-linked (GlcNAc...) asparagine	UniProt
113	N-linked (GlcNAc...) asparagine	UniProt
226	N-linked (GlcNAc...) asparagine	UniProt
297	N-linked (GlcNAc...) asparagine	UniProt
302	N-linked (GlcNAc...) asparagine	UniProt
803	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Lysosomal oligosaccharide catabolism	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Acknowledgements