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Tyrosine-protein kinase ABL2
Summary
- UniProt ID
- Q4JIM5
- Gene Symbol
- Abl2 Arg
- Gene ID
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- 3D-structure ATP-binding Acetylation Cell adhesion Cytoskeleton Magnesium Manganese Metal-binding Myristate Phosphoprotein Reference proteome SH2 domain SH3 domain Tyrosine-protein kinase Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| neural tube closure | ||
| neural tube closure | ||
| aggressive behavior | ||
| protein phosphorylation | ||
| phagocytosis |
GO Hierarchy
biological process
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| phagocytic cup | ||
| plasma membrane | ||
| actin cytoskeleton | ||
| actin cytoskeleton | ||
| lamellipodium |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| magnesium ion binding | ||
| magnesium ion binding | ||
| magnesium ion binding | ||
| phosphotyrosine residue binding | ||
| protein tyrosine kinase activity |
Sequence
MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTADAGFNVFTQHDHFASCVEDGFEGDKTGGSSPEVLHRPFGCDAESQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTFKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRTASSSSVVPYLPRLPLLPSKTRTLRKQGENKENLDGGLDAAESLASSSAPAGFIRSTQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYELTGNFSPVASLQNADGFSVAPSQQEPNLVPAKCYGGSFAQRNLCADDDSGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEEGAAPARERPKAKLLPRGATALPLRAPDPAITESDSPGVGVAGVAAAPKGKERNGGTRLGVAGVPEDGEQLGWSSPAKAVAVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSTCSDPEEEPTAPPAGQHTPETQEGGKKAAPGPVPSSGKPGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSAITEPVPNSQLVDTGHQLLDYCSGYVDSIPQTRNKFAFREAVSKLELSLQELQVSSTAAGVPGTNPVLNNLLSCVQEISDVVQR
Glycosylation Sites
G77547TA
G49108TO
G41247ZX
G84349RE
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Negative regulation of FLT3 | Mus musculus |
| RAC1 GTPase cycle | Mus musculus |
| RAC3 GTPase cycle | Mus musculus |
| Role of ABL in ROBO-SLIT signaling | Mus musculus |
