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L-dopachrome tautomerase

Summary

UniProt ID: Q4R1H1
Gene Symbol: DCT TYRP2
Gene ID: 574066
Organism: Sus scrofa (pig)

External Links

PubChem: Q4R1H1
Re-Glyco: Q4R1H1

Annotation

Keyword: Glycoprotein Isomerase Melanin biosynthesis Metal-binding Reference proteome Signal Transmembrane helix Zinc

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
positive regulation of neuroblast proliferation	IBA	GO_REF
melanin biosynthetic process from tyrosine	ISS	GO_REF
melanin biosynthetic process from tyrosine	IBA	GO_REF
melanin biosynthetic process from tyrosine	IEA	GO_REF
response to blue light	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process [inference]

melanin biosynthetic process from tyrosine

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process [inference]

melanin biosynthetic process from tyrosine

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process [inference]

melanin biosynthetic process from tyrosine

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process [inference]

melanin biosynthetic process from tyrosine

secondary metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process [inference]

melanin biosynthetic process from tyrosine

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process [inference]

melanin biosynthetic process from tyrosine

pigment metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process [inference]

melanin biosynthetic process from tyrosine

pigment biosynthetic process [inference]

melanin biosynthetic process [inference]

melanin biosynthetic process from tyrosine

primary metabolic process [inference]

amino acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

melanin biosynthetic process from tyrosine

proteinogenic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

melanin biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

L-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

melanin biosynthetic process from tyrosine

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

aromatic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

melanin biosynthetic process from tyrosine

proteinogenic amino acid metabolic process [inference]

tyrosine metabolic process [inference]

melanin biosynthetic process from tyrosine

alpha-amino acid metabolic process [inference]

L-amino acid metabolic process [inference]

tyrosine metabolic process [inference]

melanin biosynthetic process from tyrosine

cellular developmental process [inference]

cell development

cell division [inference]

forebrain ventricular zone progenitor cell division [inference]

ventricular zone neuroblast division

neuroblast division [inference]

forebrain neuroblast division [inference]

ventricular zone neuroblast division

developmental process [inference]

anatomical structure development [inference]

cell development

cellular developmental process [inference]

cell development

pigmentation [inference]

developmental pigmentation

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to blue light

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

regulation of neural precursor cell proliferation [inference]

regulation of neuroblast proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
cytosol	ISS	GO_REF
cytosol	IEA	GO_REF
plasma membrane	IEA	GO_REF
melanosome membrane	ISS	GO_REF
melanosome membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

pigment granule membrane [inference]

melanosome membrane

bounding membrane of organelle [inference]

pigment granule membrane [inference]

melanosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

Displaying **all 5** entries
GO Term	Evidence Code	Reference
dopachrome isomerase activity	ISS	GO_REF
dopachrome isomerase activity	IBA	GO_REF
dopachrome isomerase activity	IEA	GO_REF GO_REF GO_REF
oxidoreductase activity	IEA	GO_REF
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

intramolecular oxidoreductase activity, transposing C=C bonds [inference]

dopachrome isomerase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MVPFRWGLLLGCLGSALGPGAQAQFPRVCMTVGSLQAKECCPPLGAEPSNVCGSLEGRGRCAEVQADTRPWSGPYVLRNQDDRERWPRKFFDRTCRCTGNFAGYNCGDCKFGWTGPNCDQKKPLVVRQNIHSLTAQEREQFLGALDLAKNTPHPDYVITTQHWLGLLGPNGTQPQIANCSIYDLFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERALQRLTGNESFAVPYWNFATGRNECDVCTDQLLGAARPDDPTLISQNSRFSSWEIVCDSLDDYNRRVTLCNGTYEGLLRRNQVGRNSEKLPSLKDIEDCLSLKQFDNPPFFQNSTFSFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTSALPHSAANDPVFVVLHSFTDAIFDEWMKRFSPPVDAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTADQLGYSYAIDLPVSVEGTPDWTTTLSVVMGMLVVLVGLSALLLFLQYRRLRKGYTPLMETQLSHKRYTEEA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
170	N-linked (GlcNAc...) asparagine	UniProt
178	N-linked (GlcNAc...) asparagine	UniProt
237	N-linked (GlcNAc...) asparagine	UniProt
300	N-linked (GlcNAc...) asparagine	UniProt
342	N-linked (GlcNAc...) asparagine	UniProt
377	N-linked (GlcNAc...) asparagine	UniProt