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Hyaluronidase

Summary

UniProt ID: Q5BK36
Gene Symbol: Hyal5 MGC108951 rCG_28195
Gene ID: 500052
Organism: Rattus norvegicus (Norway rat)

External Links

Re-Glyco: Q5BK36

Annotation

Keyword: Cell membrane Coiled coil Disulfide bond GPI-anchor Glycosidase Reference proteome Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
carbohydrate metabolic process	IEA	GO_REF GO_REF
penetration of zona pellucida
fusion of sperm to egg plasma membrane involved in single fertilization	IEA	GO_REF
hyaluronan catabolic process	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

reproductive process [inference]

multicellular organismal reproductive process [inference]

penetration of zona pellucida

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

multicellular organismal process [inference]

multi-multicellular organism process [inference]

penetration of zona pellucida

Displaying **all 3** entries
GO Term	Evidence Code	Reference
acrosomal vesicle	IBA	GO_REF
acrosomal vesicle	IEA	GO_REF
external side of plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	Reference
hyalurononglucosaminidase activity	IBA	GO_REF
hyalurononglucosaminidase activity	IEA	GO_REF GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

hexosaminidase activity [inference]

hyalurononglucosaminidase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRVLCFKHSFFGSLLESSGLPQTLLVFLLIRCCLTVDFRAPPLIPNVPFLCAWNAPTESCATRFNQPLDLSLFSLVGSPRKTAIGHPVTIFYSDRLGLYPHIDEMHTAFHGGIPQLGSLKSHLEIAKGDIHHYMPIDNVGLAVIDWEDWRPTWSRNWKFKDIYRNKSIEFVQQQNTQLNLTEAVKRAKQEFEEAARNFMEQTLKLGKLLRPNHLWGFYLFPDCYNNNFQDANYKGDCPDIEKQRNDALFWIWKESTALYPSIYLKSSLKSSPLAALYVRNRVQEAIRMSKVKDPHNPLPIFVYFRPVFTDLTFQYLEQDDLVNTIGETVALGASGIVMWGTLNLSQTMKSCMNLHDYLKTTLNPYIINVTLAAKMCSQTLCQNQGICSRKDWNSNDYLHLSPRNFQIHFIKHGKYEIIGSPTLDDLQYFSKNFRCSCFSNLDCKERVDINHVSRVNVCTLEDICINSLVISDRSKLHDNWDHLYFANDKQSGITSSATVSPCVPRKDVSGYLFVLSLYSRHLKYSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
368	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Hyaluronan degradation	Rattus norvegicus
Interaction With Cumulus Cells And The Zona Pellucida	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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International Collaboration

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