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Lysophospholipid acyltransferase 5

Summary

UniProt ID: Q5FVN0
Gene Symbol: Grcc3f Lpcat3 Mboat5 Oact5
Gene ID: 362434
Organism: Rattus norvegicus (Norway rat)

External Links

Re-Glyco: Q5FVN0

Annotation

Keyword: Acetylation Acyltransferase Endoplasmic reticulum Glycoprotein Phospholipid biosynthesis Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	Reference
phosphatidylcholine biosynthetic process	IBA	GO_REF
lipid modification	IBA	GO_REF
chylomicron assembly	ISS	GO_REF
chylomicron assembly	ISO	GO_REF
very-low-density lipoprotein particle assembly	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine acyl-chain remodeling

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine acyl-chain remodeling

phosphatidylcholine metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine acyl-chain remodeling

phosphatidylcholine metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine acyl-chain remodeling

phosphatidylcholine metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

lipid modification

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine acyl-chain remodeling

phosphatidylcholine metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

protein-lipid complex organization [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

membrane organization [inference]

endoplasmic reticulum membrane organization

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

intestinal stem cell homeostasis

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

intestinal stem cell homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of acylglycerol transport [inference]

positive regulation of triglyceride transport

regulation of acylglycerol transport [inference]

positive regulation of acylglycerol transport [inference]

positive regulation of triglyceride transport

regulation of triglyceride transport [inference]

positive regulation of triglyceride transport

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of acylglycerol transport [inference]

positive regulation of triglyceride transport

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of acylglycerol transport [inference]

positive regulation of triglyceride transport

regulation of acylglycerol transport [inference]

positive regulation of acylglycerol transport [inference]

positive regulation of triglyceride transport

regulation of triglyceride transport [inference]

positive regulation of triglyceride transport

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of acylglycerol transport [inference]

positive regulation of triglyceride transport

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of acylglycerol transport [inference]

positive regulation of triglyceride transport

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of acylglycerol transport [inference]

positive regulation of triglyceride transport

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of response to endoplasmic reticulum stress

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of response to endoplasmic reticulum stress

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of response to endoplasmic reticulum stress

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

negative regulation of response to endoplasmic reticulum stress

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

regulation of sterol biosynthetic process [inference]

regulation of cholesterol biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of cholesterol biosynthetic process

regulation of small molecule metabolic process [inference]

regulation of cholesterol metabolic process [inference]

regulation of cholesterol biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of cholesterol biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of steroid metabolic process [inference]

regulation of steroid biosynthetic process [inference]

regulation of sterol biosynthetic process [inference]

regulation of cholesterol biosynthetic process

regulation of cholesterol metabolic process [inference]

regulation of cholesterol biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

regulation of sterol biosynthetic process [inference]

regulation of cholesterol biosynthetic process

negative regulation of cellular process [inference]

negative regulation of response to endoplasmic reticulum stress

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

negative regulation of response to endoplasmic reticulum stress

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of digestive system process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

regulation of intestinal absorption [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

regulation of intestinal lipid absorption [inference]

regulation of intestinal cholesterol absorption [inference]

positive regulation of intestinal cholesterol absorption

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of intestinal absorption [inference]

positive regulation of intestinal lipid absorption [inference]

positive regulation of intestinal cholesterol absorption

regulation of plasma lipoprotein particle levels

Displaying **all 4** entries
GO Term	Evidence Code	Reference
endoplasmic reticulum membrane	ISS	GO_REF
endoplasmic reticulum membrane	ISO	GO_REF
endoplasmic reticulum membrane	IEA	GO_REF GO_REF
membrane	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
1-acylglycerophosphocholine O-acyltransferase activity	ISS	GO_REF
1-acylglycerophosphocholine O-acyltransferase activity	ISO	GO_REF
1-acylglycerophosphocholine O-acyltransferase activity	IBA	GO_REF
1-acylglycerophosphocholine O-acyltransferase activity	IEA	GO_REF GO_REF GO_REF
lysophospholipid acyltransferase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity [inference]

lysophospholipid acyltransferase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MASTADGDVGETLGQMRGLWPGVEDLSLNKLATSLGASEQALRLIFSIFLGYPLALFYRHYLFYKDSYLIHLFHAFSGLSIAYFNFGHQFYHSLLCVVLQFLILRLMGRTITAVFTTLCFQMAYLLAGYYYTATGDYDIKWTMPHCVLTLKLIGLSIDYYDGGKDRNSLSSEQQKYAILGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVKGQLTDVPGKMPNSTIPALKRLSLGLVYLVGYTLLSPHITEDYLLTEDYDTRPFWFRCMYMLIWGKFVLYKYVTCWLVTEGVCILSGLGFNGFEENGTVKWDACANMKVWLFETTPRFTGTIASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLICFQMEFLIVIVEKQATNLIRDSPALSSLASITALQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYRSIYFLGHVFFLSLLFTLPYVYKAMVPRKEKLKKRE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
308	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Acyl chain remodelling of PC	Rattus norvegicus
Acyl chain remodelling of PE	Rattus norvegicus
Acyl chain remodelling of PS	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements