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Neurocan core protein

Summary

UniProt ID: Q5IS41
Gene Symbol: NCAN CSPG3
Gene ID: 468775
Organism: Pan troglodytes (chimpanzee)

External Links

Re-Glyco: Q5IS41

Annotation

Keyword: Calcium Cell adhesion Disulfide bond EGF-like domain Hyaluronic acid Immunoglobulin domain Lectin Proteoglycan Reference proteome Repeat Secreted Signal Sushi

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
skeletal system development	IBA	GO_REF
cell adhesion	IEA	GO_REF
central nervous system development	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

developmental process [inference]

anatomical structure development [inference]

system development [inference]

animal gross anatomical part developmental process [inference]

Displaying **all 5** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
Golgi lumen	IEA	GO_REF
lysosomal lumen	IEA	GO_REF
synapse	IBA	GO_REF
perineuronal net	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix [inference]

specialized extracellular matrix [inference]

synapse-associated extracellular matrix [inference]

perisynaptic extracellular matrix [inference]

perineuronal net

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

Golgi lumen

Displaying **all 3** entries
GO Term	Evidence Code	Reference
calcium ion binding	IEA	GO_REF
hyaluronic acid binding	IEA	GO_REF
carbohydrate binding

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

hyaluronic acid binding

cation binding [inference]

metal ion binding [inference]

calcium ion binding

organic acid binding [inference]

carboxylic acid binding [inference]

hyaluronic acid binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGTPFVWALGLLMLQMLLFVAGEQGTQDIADASERGLHMQKLGSGSVQAALAELVALPCLFTLQPQPSAARDAPRIKWTKVRTASGQRQDLPILVAKDNVVKVAKSWQGRVSLPSYPRRRANATLLLGPLRASDSGLYRCQVVRGIEDEQDLVPLEVTGVVFHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPITQSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCRRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANRTGFPSPAERFDAYCFRAHHPTSQHGDLETPSSGDEGEILSAEGPPVRELEPTLEEEEVVTPDFQEPLVSSGEEEPLILEEKQESQQTLSPTPGDPMLASWPTGEVWLSTVAPSPSDMGAGTAASSHTEVAPTDPMPRRRGRFKGLNGRYFQQQEPEPGLQGGMEASAQPPTSEAAGNQMEPPLAMAVTEMLGSGQSRSPWADLTNEVDMPGAGSAGGKSSPEPWLWPPTMVPPSISGHSRAPVLELEKAEGPSARPATPDLFWSPLEATVSAPSPAPWEAFPVATSPDLPMMAMLRGPKEWMLPHPTPISTEANRVEAHGEATTTPPPSPAAETKVYSLPLSLTPTGQGGEAMPTTPESPGADFRETGETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETATEPTGLRGISGSESGVLDTAESPTSGLQATVDEVQDPWPSVYSKGLGASSPSAPLGSPGVFLVPKVTPSLEPWVATDEGPTVNPMDSTVTLAPSDASGIWEPGSQVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTLGSSSSQPHPEPEDQVETQGTSGASVPPHQSSPLGKPAVPPGTPTAASVGESASVSSGEPTVPWDPSSTLLPVTLGIEDFELEVLAGSPGVESFWEEVASGEEPALPGTPMKAGAEEVHSDPCENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAERDCRRRSGHLTSVHSSEEHSFINSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHHVATIRCRSNGKWDRPQIVCTKPRRSHRMRRHHHHHQHHHQHHHHKSRKERRKHKKHPTEDWEKDEGNFC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
122	N-linked (GlcNAc...) asparagine	UniProt
340	N-linked (GlcNAc...) asparagine	UniProt
381	O-linked (Xyl...) (chondroitin sulfate) serine	UniProt
411	O-linked (Xyl...) (chondroitin sulfate) serine	UniProt
1026	N-linked (GlcNAc...) asparagine	UniProt
1223	N-linked (GlcNAc...) asparagine	UniProt