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MIRAGE

Cationic amino acid transporter 2

Summary

UniProt ID: Q5PR34
Gene Symbol: slc7a2 zgc:103686
Gene ID: 494041
Organism: Danio rerio (zebrafish)

External Links

PubChem: Q5PR34
Re-Glyco: Q5PR34

Annotation

Keyword: Amino-acid transport Cell membrane Glycoprotein Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
L-arginine import across plasma membrane	IBA	GO_REF
L-ornithine transmembrane transport	IBA	GO_REF
L-arginine transmembrane transport	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

L-arginine import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-alpha-amino acid transmembrane transport [inference]

ornithine transport [inference]

L-ornithine transmembrane transport

organic cation transport [inference]

ornithine transport [inference]

L-ornithine transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

L-amino acid transport [inference]

L-alpha-amino acid transmembrane transport [inference]

ornithine transport [inference]

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

L-amino acid transport [inference]

L-alpha-amino acid transmembrane transport [inference]

ornithine transport [inference]

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

L-arginine import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

nitrogen compound transport [inference]

L-amino acid transport [inference]

L-alpha-amino acid transmembrane transport [inference]

ornithine transport [inference]

L-ornithine transmembrane transport

import into cell [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

L-arginine import across plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	Reference
L-ornithine transmembrane transporter activity	IBA	GO_REF
L-lysine transmembrane transporter activity	IBA	GO_REF
L-arginine transmembrane transporter activity	IBA	GO_REF
L-arginine transmembrane transporter activity	IEA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

basic amino acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLEHCLTFGRSLVRRKNVDQGCLEESKLCRCLSTVDLIALGVGSTLGAGVYVLAGEVAKGSSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDEIIGGHIEKFCKMYFKMSLPGLAEYPDFFAVCLILLLSGLLSFGVKESAWVNKIFTAVNVLVLMFVIISGFVKGDSLNWNISEESLVNITVVKRNISSAANVTSDYGAGGFFPYGFGGTLAGAATCFYAFVGFDCIATTGEEVKNPQRAIPIGIVVSLLVCFLAYFGVSAALTLMMPYYLLDEKSPLPLAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGVLFRFLSKLSKRQSPVAATMAAGTTAAIMAFLFDLKALVDMMSIGTLLAYSLVAACVLILRYQPDASFERSRISEGKEEVGESELTESESHLNMLKDGGVTLRSLLHPPLLPTENTSSVVNVSVIITVLVVCVVSTLNTYYGQAIIAMELWALGVLAASLFIFIICVFLICRQPQTRKKVSFMVPLLPFLPILSIFVNVYLMVQLSGDTWIRFSIWMAIGFLIYFGYGMWHSDERKRHLQNCAVATEKKTLTGNEGFVENKTHTEKTSPC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
217	N-linked (GlcNAc...) asparagine			UniProt
225	N-linked (GlcNAc...) asparagine			UniProt
232	N-linked (GlcNAc...) asparagine			UniProt
238	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Amino acid transport across the plasma membrane	Danio rerio

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026