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Endoplasmic reticulum aminopeptidase 2

Summary

UniProt ID

Q5RFP3

Gene Symbol

ERAP2

Gene ID

100171433

Organism

Pongo abelii (Sumatran orangutan)

External Links

Re-Glyco: Q5RFP3

Annotation

Keyword: Adaptive immunity Aminopeptidase Disulfide bond Endoplasmic reticulum Glycoprotein Metal-binding Metalloprotease Reference proteome Signal-anchor Transmembrane helix Zinc

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
adaptive immune response
proteolysis	IEA	GO_REF GO_REF
regulation of blood pressure	IEA	GO_REF
antigen processing and presentation of endogenous peptide antigen via MHC class I	IEA	GO_REF
peptide catabolic process	IEA	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

antigen processing and presentation [inference]

antigen processing and presentation of endogenous antigen [inference]

antigen processing and presentation of endogenous peptide antigen [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I

antigen processing and presentation of peptide antigen [inference]

antigen processing and presentation of peptide antigen via MHC class I [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I

antigen processing and presentation of endogenous peptide antigen [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I

cellular process [inference]

metabolic process [inference]

peptide metabolic process [inference]

peptide catabolic process

catabolic process [inference]

peptide catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

response to stimulus [inference]

immune response [inference]

adaptive immune response

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure

Displaying **all 2** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
endoplasmic reticulum membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
zinc ion binding	IEA	GO_REF GO_REF
peptide binding	IEA	GO_REF
metalloaminopeptidase activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity [inference]

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity [inference]

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity [inference]

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity [inference]

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

peptide binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLHSSAMVNSHRKSMFNIHKGFYCLAAILPQICICSQFSVPSSYHFSEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHQQIALLVPEKLMPHLKYYVAIDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESGHIALSNMPKVRTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSVSGITSSGVKVSIYASPDKQNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFASGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLTFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTHYLQHETSSPALLEGLSYLELFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDEGSVWDRMLRSALLKLACDLNHAPCIQKATELFSQWMESSGKLNIPTDVLKIVYSVGAQTAAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHVIARRPKGQQLAWDFVRENWTHLLKKFDLGSFDIRMIISGTTARFSSKDKLQEVKLFFESLEAQGSHLDIFQIVLETITKNIKWLEKNLPTLRTWLLVNT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
85	N-linked (GlcNAc...) asparagine	UniProt
119	N-linked (GlcNAc...) asparagine	UniProt
405	N-linked (GlcNAc...) asparagine	UniProt
650	N-linked (GlcNAc...) asparagine	UniProt