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Interleukin-23 receptor
Summary
- UniProt ID
- Q5VWK5
- Gene Symbol
-
- IL23R
- Gene ID
- 149233
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Glycoprotein
- Inflammatory response
- Innate immunity
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| receptor complex |
| external side of plasma membrane |
| cell surface |
| interleukin-23 receptor complex |
| GO Term |
|---|
| cytokine receptor activity |
| cytokine binding |
Sequence
MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQPRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMNNNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSLSNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGIVNEELPSINTYFPQNILESHFNRISLLEK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 29 | N-linked (GlcNAc...) asparagine; partial |
|
||
| 47 | N-linked (GlcNAc...) asparagine |
|
||
| 58 |
|
|
||
| 81 | N-linked (GlcNAc...) asparagine |
|
||
| 141 | N-linked (GlcNAc...) asparagine |
|
||
| 180 | N-linked (GlcNAc...) (high mannose) asparagine |
|
||
| 232 | N-linked (GlcNAc...) asparagine |
|
||
| 262 | N-linked (GlcNAc...) asparagine |
|
||
| 273 | N-linked (GlcNAc...) asparagine; partial |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-23 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081120 | Graves ophthalmopathy | |
| DOID:0110883 | inflammatory bowel disease 17 | |
| DOID:0111279 | psoriasis 7 | |
| DOID:10159 | osteonecrosis | |
| DOID:10608 | celiac disease | |
| DOID:11335 | sarcoidosis | |
| DOID:12361 | Graves' disease | |
| DOID:13141 | uveitis | |
| DOID:13241 | Behcet's disease | |
| DOID:2377 | multiple sclerosis |
