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Sodium-dependent phosphate transport protein 2A

Summary

UniProt ID: Q60825
Gene Symbol: Slc34a1 Npt2 Slc17a2
Gene ID
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0005418
GlyGen: Q60825
PubChem: Q60825
Re-Glyco: Q60825

Annotation

Keyword: Cell membrane Disulfide bond Glycoprotein Phosphoprotein Reference proteome Sodium transport Symport Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	Reference
phosphate ion transport	ISO	GO_REF
response to lead ion	ISO	GO_REF
gene expression	IMP	PMID
cellular response to phosphate starvation	ISO	GO_REF
inorganic diphosphate transport	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

phosphate ion transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

arsenate ion transmembrane transport

multicellular organismal process [inference]

tissue remodeling [inference]

bone remodeling

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular phosphate ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular phosphate ion homeostasis

inorganic ion homeostasis [inference]

phosphate ion homeostasis

intracellular phosphate ion homeostasis

calcium ion homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to chemical [inference]

response to metal ion [inference]

response to salt [inference]

response to sodium phosphate

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic anion transport [inference]

phosphate ion transport

inorganic diphosphate transport

arsenite transport [inference]

arsenate ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

phosphate ion transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

arsenate ion transmembrane transport

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of phosphate transport [inference]

regulation of sodium-dependent phosphate transport [inference]

positive regulation of sodium-dependent phosphate transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of sodium-dependent phosphate transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of sodium-dependent phosphate transport

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of biological quality [inference]

regulation of membrane potential [inference]

positive regulation of membrane potential

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	Reference
nucleoplasm	ISO	GO_REF
endosome	ISO	GO_REF
cytosol	ISO	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	ISO	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

spindle [inference]

mitotic spindle

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membraneless organelle [inference]

spindle [inference]

mitotic spindle

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

perinuclear region of cytoplasm

cluster of actin-based cell projections [inference]

brush border

supramolecular complex [inference]

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
sodium:phosphate symporter activity	ISS	GO_REF
sodium:phosphate symporter activity	ISO	GO_REF GO_REF
sodium:phosphate symporter activity	EXP	PMID
sodium:phosphate symporter activity	IDA	PMID
sodium:phosphate symporter activity	IBA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

phosphate transmembrane transporter activity [inference]

sodium:phosphate symporter activity

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

binding [inference]

protein binding [inference]

protein domain specific binding [inference]

PDZ domain binding

identical protein binding

protein-containing complex binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MMSYSERLGGPAVSPLPVRGRHMVHGATFAYVPSPQVLHRIPGTSTYAISSLSPVTLTEHSCPCGEVLECHDPLPTKLAQEEEQKPEPRLSQKLAQVGTKLLKVPLMLAFLYLFVCSLDVLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHVTGLVVASFNIRGGRDAPDLLKVITEPFTRLIIQLDKSVITSIAVGDESLRNHSLIRIWCHPDTTEASTSMSRVEAIGSLANTTMEKCNHIFVDTGLPDLAVGLILLAGSLVVLCTCLILLVKMLNSLLKGQVMSSRRSSTQTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSSFQIALCHFFFNISGILLWYPLPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQAMVGVGTPFGALLAFVVLVNVLQSRSPGHLPKWLQTWDFLPRWMHSLQPLDGLITRATLCYARPEPRSPQLPPRVFLEELPPATPSPRLALPAHHNATRL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
298	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt GlyGen
328	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt GlyGen
621		GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Surfactant metabolism	Mus musculus
Type II Na+/Pi cotransporters	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050947	hereditary hypophosphatemic rickets with hypercalciuria	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements