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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Receptor-interacting serine/threonine-protein kinase 1
Summary
- UniProt ID
- Q60855
- Gene Symbol
-
- Ripk1
- Rinp
- Rip
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Apoptosis
- Cell membrane
- Cytoplasm
- Host-virus interaction
- Inflammatory response
- Isopeptide bond
- Necrosis
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of extrinsic apoptotic signaling pathway |
| positive regulation of extrinsic apoptotic signaling pathway |
| amyloid fibril formation |
| GO Term |
|---|
| protein-containing complex |
| receptor complex |
| death-inducing signaling complex |
| mitochondrion |
| ripoptosome |
| GO Term |
|---|
| protein serine/threonine kinase activity |
Sequence
MQPDMSLDNIKMASSDLLEKTDLDSGGFGKVSLCYHRSHGFVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAIPEDRPTFLGIEEEFRPFYLSHFEEYVEEDVASLKKEYPDQSPVLQRMFSLQHDCVPLPPSRSNSEQPGSLHSSQGLQMGPVEESWFSSSPEYPQDENDRSVQAKLQEEASYHAFGIFAEKQTKPQPRQNEAYNREEERKRRVSHDPFAQQRARENIKSAGARGHSDPSTTSRGIAVQQLSWPATQTVWNNGLYNQHGFGTTGTGVWYPPNLSQMYSTYKTPVPETNIPGSTPTMPYFSGPVADDLIKYTIFNSSGIQIGNHNYMDVGLNSQPPNNTCKEESTSRHQAIFDNTTSLTDEHLNPIRENLGRQWKNCARKLGFTESQIDEIDHDYERDGLKEKVYQMLQKWLMREGTKGATVGKLAQALHQCCRIDLLNHLIRASQS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Mus musculus |
| Dimerization of procaspase-8 | Mus musculus |
| IKK complex recruitment mediated by RIP1 | Mus musculus |
| Ligand-dependent caspase activation | Mus musculus |
| Ovarian tumor domain proteases | Mus musculus |
| RIPK1-mediated regulated necrosis | Mus musculus |
| Regulation by c-FLIP | Mus musculus |
| Regulation of TNFR1 signaling | Mus musculus |
| Regulation of necroptotic cell death | Mus musculus |
| TNF signaling | Mus musculus |
