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Double-strand break repair protein MRE11

Summary

UniProt ID

Q61216

Gene Symbol

Mre11
Mre11a

Gene ID

[17535]

Organism

Mus musculus (house mouse)

External Links

PubChem: Q61216
The O-GlcNAc Database: Q61216
Re-Glyco: Q61216

Annotation

Keyword: Acetylation Alternative splicing DNA repair Endonuclease Exonuclease Isopeptide bond Manganese Meiosis Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Telomere Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 53 in total

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GO Term	Evidence Code	Reference
telomere maintenance	IBA	GO_REF
double-strand break repair via homologous recombination	ISS	GO_REF
double-strand break repair via homologous recombination	ISO	GO_REF
double-strand break repair via homologous recombination	IMP	PMID
double-strand break repair via homologous recombination	IBA	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response [inference]

host-mediated suppression of symbiont invasion

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair

mitochondrial double-strand break repair [inference]

mitochondrial double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

homologous recombination

DNA strand elongation [inference]

telomeric 3' overhang formation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair

mitochondrial double-strand break repair [inference]

mitochondrial double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

homologous recombination

DNA strand elongation [inference]

telomeric 3' overhang formation

cell population proliferation

cell cycle process [inference]

sister chromatid cohesion

meiotic cell cycle process [inference]

meiosis I cell cycle process [inference]

meiotic DNA double-strand break formation

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

mitotic cell cycle process [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

recombinational repair [inference]

double-strand break repair

mitochondrial double-strand break repair [inference]

mitochondrial double-strand break repair via homologous recombination

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

R-loop processing

organelle organization [inference]

chromosome organization

sister chromatid cohesion

telomere organization [inference]

telomere maintenance

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

reproductive process [inference]

meiotic cell cycle process [inference]

meiosis I cell cycle process [inference]

meiotic DNA double-strand break formation

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

host-mediated perturbation of symbiont process [inference]

host-mediated suppression of symbiont invasion

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

host-mediated suppression of symbiont invasion

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

host-mediated suppression of symbiont invasion

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

recombinational repair [inference]

double-strand break repair

mitochondrial double-strand break repair [inference]

mitochondrial double-strand break repair via homologous recombination

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

immune response [inference]

innate immune response [inference]

host-mediated suppression of symbiont invasion

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

host-mediated suppression of symbiont invasion

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

host-mediated suppression of symbiont invasion

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

recombinational repair [inference]

double-strand break repair

mitochondrial double-strand break repair [inference]

mitochondrial double-strand break repair via homologous recombination

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

positive regulation of response to stimulus [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of response to stimulus [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

negative regulation of response to stimulus [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of double-strand break repair

regulation of double-strand break repair via nonhomologous end joining [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of DNA metabolic process [inference]

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of double-strand break repair

regulation of double-strand break repair via nonhomologous end joining [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of DNA metabolic process [inference]

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of double-strand break repair

regulation of double-strand break repair via nonhomologous end joining [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

regulation of chromosome organization [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic DNA integrity checkpoint signaling [inference]

mitotic DNA damage checkpoint signaling [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

mitotic G2 DNA damage checkpoint signaling

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of double-strand break repair

regulation of double-strand break repair via nonhomologous end joining [inference]

negative regulation of double-strand break repair via nonhomologous end joining

Displaying entries **1 - 5** of 32 in total

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GO Term	Evidence Code	Reference
chromosome, telomeric region	ISO	GO_REF
chromosome, telomeric region	IDA	PMID
chromosome, telomeric region	IEA	GO_REF GO_REF
chromatin	ISO	GO_REF
condensed nuclear chromosome	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

chromosome [inference]

nuclear chromosome [inference]

condensed nuclear chromosome

condensed chromosome [inference]

condensed nuclear chromosome

nuclear body [inference]

PML body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

chromosome [inference]

nuclear chromosome [inference]

condensed nuclear chromosome

condensed chromosome [inference]

condensed nuclear chromosome

nuclear body [inference]

PML body

perinuclear region of cytoplasm

site of DNA damage [inference]

site of double-strand break

chromosomal region

chromosome, telomeric region

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	Reference
single-stranded DNA endonuclease activity	ISO	GO_REF
single-stranded DNA endonuclease activity	IBA	GO_REF
single-stranded DNA endonuclease activity	IEA	GO_REF
DNA binding	ISO	GO_REF
DNA binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

single-stranded DNA endonuclease activity

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-DNA exonuclease activity

3'-5' exonuclease activity

3'-5'-DNA exonuclease activity

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

nucleic acid conformation isomerase activity [inference]

helicase activity [inference]

DNA helicase activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity [inference]

DNA helicase activity

nuclease activity

endonuclease activity [inference]

endodeoxyribonuclease activity

single-stranded DNA endonuclease activity

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-DNA exonuclease activity

3'-5' exonuclease activity

3'-5'-DNA exonuclease activity

DNA nuclease activity [inference]

endodeoxyribonuclease activity

single-stranded DNA endonuclease activity

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-DNA exonuclease activity

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

endodeoxyribonuclease activity

single-stranded DNA endonuclease activity

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-DNA exonuclease activity

ATP-dependent activity, acting on DNA [inference]

DNA helicase activity

binding [inference]

nucleic acid binding [inference]

DNA binding

protein binding [inference]

identical protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

ATP-dependent activity [inference]

helicase activity [inference]

DNA helicase activity

ATP-dependent activity, acting on DNA [inference]

DNA helicase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSPTDPLDDEDTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGDLFHENKPSRKTLHSCLELLRKYCMGDRPVQFEVISDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYGLGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGNTNFIPEQFLDDFIDLVIWGHEHECKIGPIKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMQKLPLRTVRRFFIEDVVLANHPNLFNPDNPKVTQAIQSFCLEKIEEMLDSAERERLGNPQQPGKPLIRLRVDYSGGFEPFNVLRFSQKFVDRVANPKDVIHFFRHREQKGKTGEEINFGMLITKPASEGATLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRESRQRNTNEEDDEVREAMSRARALRSQSETSTSAFSAEDLSFDTSEQTANDSDDSLSAVPSRGRGRGRGRRGARGQSSAPRGGSQRGRDTGLEITTRGRSSKATSSTSRNMSIIDAFRSTRQQPSRNVAPKNYSETIEVDDSDEDDIFPTNSRADQRWSGTTSSKRMSQSQTAKGVDFESDEDDDDDPFMSSSCPRRNRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
625		40021952	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Cytosolic sensors of pathogen-associated DNA	Mus musculus
DNA Damage/Telomere Stress Induced Senescence	Mus musculus
G2/M DNA damage checkpoint	Mus musculus
HDR through Homologous Recombination (HRR)	Mus musculus
HDR through MMEJ (alt-NHEJ)	Mus musculus
HDR through Single Strand Annealing (SSA)	Mus musculus
Homologous DNA Pairing and Strand Exchange	Mus musculus
Nonhomologous End-Joining (NHEJ)	Mus musculus
Presynaptic phase of homologous DNA pairing and strand exchange	Mus musculus
Processing of DNA double-strand break ends	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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