GlyCosmos Portal

Submissions

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Summary

UniProt ID: Q61239
Gene Symbol: Fnta
Gene ID: 14272
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q61239
PubChem: Q61239
O-GlcNAcAtlas: Q61239
Re-Glyco: Q61239

Annotation

Keyword: Acetylation Magnesium Phosphoprotein Prenyltransferase Reference proteome Repeat

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	Reference
nuclear envelope organization	ISO	GO_REF
enzyme-linked receptor protein signaling pathway	IDA	PMID PMID
enzyme-linked receptor protein signaling pathway	IMP	PMID
enzyme-linked receptor protein signaling pathway	IGI	PMID
peptide pheromone maturation	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein prenylation [inference]

protein maturation

peptide pheromone maturation

macromolecule modification [inference]

protein modification process [inference]

protein prenylation [inference]

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein prenylation [inference]

protein maturation

peptide pheromone maturation

prenylation [inference]

protein prenylation [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

nuclear envelope organization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rac protein signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of cell cycle

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rac protein signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rac protein signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

regulation of microtubule-based process [inference]

regulation of microtubule-based movement

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rac protein signal transduction

positive regulation of cell cycle

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cell cycle [inference]

positive regulation of cell cycle

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
cytoplasm
microtubule associated complex	ISO	GO_REF
microtubule associated complex	IEA	GO_REF
CAAX-protein geranylgeranyltransferase complex	ISS	GO_REF
CAAX-protein geranylgeranyltransferase complex	ISO	PMID GO_REF GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex

intracellular protein-containing complex [inference]

CAAX-protein geranylgeranyltransferase complex

catalytic complex [inference]

transferase complex [inference]

cellular anatomical structure [inference]

cytoplasm

Displaying entries **1 - 5** of 25 in total

1

2

3

4

5

Next ›

Last »
GO Term	Evidence Code	Reference
protein farnesyltransferase activity	ISS	GO_REF
protein farnesyltransferase activity	ISO	GO_REF GO_REF
protein farnesyltransferase activity	IDA	PMID
protein farnesyltransferase activity	IMP	PMID
protein farnesyltransferase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring alkyl or aryl (other than methyl) groups [inference]

prenyltransferase activity [inference]

protein prenyltransferase activity [inference]

protein farnesyltransferase activity

protein geranylgeranyltransferase activity

catalytic activity, acting on a protein [inference]

protein prenyltransferase activity [inference]

protein farnesyltransferase activity

protein geranylgeranyltransferase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor tyrosine kinase binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

enzyme binding

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

molecular adaptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

acetyltransferase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

acetyltransferase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAATEGVGESAAGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILSQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDVYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHCRESDIPASV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
233			G31852PQ	GlyGen
376			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Apoptotic cleavage of cellular proteins	Mus musculus
GBP-mediated host defense	Mus musculus
Inactivation, recovery and regulation of the phototransduction cascade	Mus musculus
RAS processing	Mus musculus