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Receptor tyrosine-protein kinase erbB-3

Summary

UniProt ID

Q61526

Gene Symbol

Erbb3

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0005493

GlyConnect

2676

GlyGen

Q61526

PubChem

Q61526

Annotation

Keyword

ATP-binding
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

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GO Term
ERBB2-ERBB3 signaling pathway
negative regulation of secretion
Schwann cell differentiation
Schwann cell development
cranial nerve development
neurogenesis
myelination
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
neuron apoptotic process

Displaying **all 9** entries
GO Term
basal plasma membrane
ERBB3:ERBB2 complex
extracellular space
plasma membrane
postsynaptic membrane
receptor complex
basolateral plasma membrane
apical plasma membrane
lateral plasma membrane

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GO Term
protein tyrosine kinase activator activity
ubiquitin protein ligase binding
identical protein binding
ErbB-3 class receptor binding
protein heterodimerization activity
ATP binding
neuregulin receptor activity
neuregulin binding
protein kinase activity
transmembrane signaling receptor activity

Annotation information from UniProt.

Sequence

MSAIGTLQVLGFLLSLARGSEMGNSQAVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVKNNGGNCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCNGRCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQTFCVRACPADKMEVDKNGLKMCEPCRGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPAEERLDIKYNRPLGECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEPREFVHEAHCFSCHPECQPMEGTSTCNGSGSDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCKGPELQDCLGQAEVLMSKPHLVIAVTVGLTVIFLILGGSFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRASGPGIPPAAEPSALSTKELQDAELEPDLDLDLDVEVEEEGLATTLGSALSLPTGTLTRPRGSQSLLSPSSGYMPMNQSNLGEACLDSAVLGGREQFSRPISLHPIPRGRQTSESSEGHVTGSEAELQERVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLEEEDGNGYVMPDTHLRGTSSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRKRRGSPARPPRPGSLEELGYEYMDVGSDLSASLGSTQSCPLHPMAIVPSAGTTPDEDYEYMNRRRGAGGSGGDYAAMGACPAAEQGYEEMRAFQGPGHQAPHVRYARLKTLRSLEATDSAFDNPDYWHSRLFPKANAQRI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	GlyTouCan ID	Source
126	N-linked (GlcNAc...) asparagine		UniProt GlyGen
250	N-linked (GlcNAc...) asparagine	G10486CT G05724UK G39188ZX G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
353	N-linked (GlcNAc...) asparagine	G80920RR	UniProt GlyGen
408	N-linked (GlcNAc...) asparagine		UniProt GlyGen
414	N-linked (GlcNAc...) asparagine		UniProt GlyGen
437	N-linked (GlcNAc...) asparagine	G62765YT	GlycoProtDB UniProt GlyGen
469	N-linked (GlcNAc...) asparagine		UniProt GlyGen
522	N-linked (GlcNAc...) asparagine		UniProt GlyGen
566	N-linked (GlcNAc...) asparagine	G72747WU	GlycoProtDB UniProt GlyGen
608			GlycoProtDB