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Clathrin coat assembly protein AP180

Summary

UniProt ID: Q61548
Gene Symbol: Snap91
Gene ID: 20616
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q61548
The O-GlcNAc Database: Q61548
O-GlcNAcAtlas: Q61548
Re-Glyco: Q61548

Annotation

Keyword: Alternative splicing Cell membrane Coated pit Glycoprotein Methylation Phosphoprotein Protein transport Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	Reference
vesicle budding from membrane	IBA	GO_REF
establishment or maintenance of cell polarity	ISO	GO_REF
chemical synaptic transmission	IMP	PMID
neurotransmitter secretion	IMP	PMID
axonogenesis	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

establishment or maintenance of cell polarity

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular developmental process [inference]

cell development [inference]

neuron development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle budding from membrane

cellular component assembly [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

membrane organization [inference]

vesicle budding from membrane

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

developmental process [inference]

anatomical structure morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

anatomical structure development [inference]

cell development [inference]

neuron development

cellular developmental process [inference]

cell development [inference]

neuron development

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

protein transport

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

secretion [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

neurotransmitter secretion

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle clustering

regulation of protein transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of synaptic vesicle recycling [inference]

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

regulation of synaptic vesicle clustering [inference]

positive regulation of synaptic vesicle clustering

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle clustering

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

regulation of clathrin coat assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

regulation of clathrin coat assembly [inference]

positive regulation of clathrin coat assembly

regulation of synapse organization [inference]

regulation of presynapse organization [inference]

regulation of terminal button organization

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	Reference
cytosol	ISO	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IEA	GO_REF
clathrin-coated pit	IBA	GO_REF
clathrin-coated pit	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

AP-type membrane coat adaptor complex [inference]

clathrin adaptor complex [inference]

AP-2 adaptor complex

plasma membrane protein complex [inference]

AP-2 adaptor complex

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

extrinsic component of membrane [inference]

extrinsic component of plasma membrane [inference]

extrinsic component of synaptic membrane [inference]

extrinsic component of presynaptic membrane [inference]

extrinsic component of presynaptic endocytic zone membrane

cell junction [inference]

synapse [inference]

excitatory synapse [inference]

parallel fiber to Purkinje cell synapse

Schaffer collateral - CA1 synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

postsynaptic specialization [inference]

postsynaptic density

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

presynapse [inference]

axon terminus

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	Reference
SNARE binding	ISO	GO_REF
inositol hexakisphosphate binding	ISO	GO_REF
1-phosphatidylinositol binding	IDA	PMID
1-phosphatidylinositol binding	IBA	GO_REF
1-phosphatidylinositol binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

SNARE binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

phospholipase binding

protein domain specific binding [inference]

SH2 domain binding

clathrin binding

clathrin heavy chain binding

lipid binding [inference]

phospholipid binding [inference]

1-phosphatidylinositol binding

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

inositol hexakisphosphate binding

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

alcohol binding [inference]

inositol hexakisphosphate binding

molecular adaptor activity

protein-macromolecule adaptor activity [inference]

cargo adaptor activity [inference]

clathrin-cargo adaptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

lipase inhibitor activity [inference]

phospholipase inhibitor activity [inference]

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

lipase inhibitor activity [inference]

phospholipase inhibitor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMADTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDMSTFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMVPEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRFLTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDIFATASAAAPVSSAKPSSDLLDLQPDFSGAAAGAAAPVVPPSGGATAWGDLLGEDSLAALSSVPCEAPISDPFAPEPSPPTTTTEPASASASTTTAVTAVTTEVDLFGDAFAASPGEAPAASEGATAPATPAPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSAPVVTPTASTAPPVPATAPSPAPTAVAATAATTTAAAAATTTATTSAAAATTAAAPPALDIFGDLFDSAPEVAAAPKPDAAPSIDLFGTDAFSSPPRGASPVPESSLTADLLSVDAFAAPSPASTASPAKAESSGVIDLFGDAFGSGASETQPAPQAVSSSSASADLLAGFGGSFMAPSTTPVTPAQNNLLQPSFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPSGQPAPVSMVPPSPAMAASKGLGSDLDSSLASLVGNLGISGTTSKKGDLQWNAGEKKLTGGANWQPKVTPATWSAGVPPQGTVPPTSSVPPGAGAPSVGQPGAGFGMPPSGTGMTMMSQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTPATQSPKKPPAKDPLADLNIKDFL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 19 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
105			G45816RQ	GlyGen
303		22517741 22645316 22826440 26192747 30059200 33300544 34678516 35822049 36852467 40885482	G49108TO	GlyGen The O-GlcNAc Database
305		22517741 22645316 22826440 26192747 30059200 33300544 34678516 35822049 36852467 40885482	G49108TO	The O-GlcNAc Database
306		22517741 22645316 22826440 26192747 30059200 33300544 34678516 35822049 36852467 40885482	G49108TO	The O-GlcNAc Database
309		22517741 22645316 22826440 26192747 30059200 33300544 34678516 35822049 36852467 40885482	G49108TO	GlyGen The O-GlcNAc Database
310	O-linked (GlcNAc) threonine	22517741 22645316 22826440 26192747 30059200 33300544 34678516 35822049 36852467 40885482	G49108TO	UniProt GlyGen The O-GlcNAc Database
312		22517741 22645316 22826440 26192747 30059200 33300544 34678516 35822049 36852467 40885482	G49108TO	GlyGen The O-GlcNAc Database
317				GlyGen
333			G49108TO	GlyGen
459				GlyGen