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Macrophage mannose receptor 1

Summary

UniProt ID: Q61830
Gene Symbol: Mrc1
Gene ID: 17533
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0005534
GlyGen: Q61830
PubChem: Q61830
Re-Glyco: Q61830

Annotation

Keyword: 3D-structure Calcium Cell membrane Disulfide bond Endocytosis Endosome Glycoprotein Lectin Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
receptor-mediated endocytosis	ISS	GO_REF
receptor-mediated endocytosis	ISO	GO_REF
receptor-mediated endocytosis	IBA	GO_REF
receptor-mediated endocytosis	IEA	GO_REF
cellular response to lipopolysaccharide	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to chemical [inference]

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to peptide [inference]

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

response to interleukin-4 [inference]

cellular response to interleukin-4

cellular response to cytokine stimulus [inference]

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	TAS	Reactome
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
transmembrane signaling receptor activity	IDA	PMID
transmembrane signaling receptor activity	IBA	GO_REF
D-mannose binding	IDA	PMID
D-mannose binding	IEA	GO_REF
signaling receptor activity

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

D-mannose binding

small molecule binding [inference]

monosaccharide binding [inference]

D-mannose binding

cargo receptor activity

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRLLLLLAFISVIPVSVQLLDARQFLIYNEDHKRCVDALSAISVQTATCNPEAESQKFRWVSDSQIMSVAFKLCLGVPSKTDWASVTLYACDSKSEYQKWECKNDTLFGIKGTELYFNYGNRQEKNIKLYKGSGLWSRWKVYGTTDDLCSRGYEAMYSLLGNANGAVCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDKDKLFGFCPLHFEGSERLWNKDPLTGILYQINSKSALTWHQARASCKQQNADLLSVTEIHEQMYLTGLTSSLSSGLWIGLNSLSVRSGWQWAGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNNTLNPFIIPSASDVPTGCPNQWWPYAGHCYRIHREEKKIQKYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCVVMKGKDGYWADRACEQPLGYICKMVSQSHAVVPEGADKGCRKGWKRHGFYCYLIGSTLSTFTDANHTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGTFRWTVDEQVQFTHWNADMPGRKAGCVAMKTGVAGGLWDVLSCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPENWGTTSKTSMCFKLYAKGKHEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRLITSSGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLNNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDYQYYFSKEKETMDNARAFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGMLISMDKKFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGYPNNFICQRHNSSINATAMPTTPTTPGGCKEGWHLYKNKCFKIFGFANEEKKSWQDARQACKGLKGNLVSIENAQEQAFVTYHMRDSTFNAWTGLNDINAEHMFLWTAGQGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNSREAGTWMDDTCDSKQGYICQTQTDPSLPVSPTTTPKDGFVTYGKSSYSLMKLKLPWHEAETYCKDHTSLLASILDPYSNAFAWMKMHPFNVPIWIALNSNLTNNEYTWTDRWRVRYTNWGADEPKLKSACVYMDVDGYWRTSYCNESFYFLCKKSDEIPATEPPQLPGKCPESEQTAWIPFYGHCYYFESSFTRSWGQASLECLRMGASLVSIETAAESSFLSYRVEPLKSKTNFWIGMFRNVEGKWLWLNDNPVSFVNWKTGDPSGERNDCVVLASSSGLWNNIHCSSYKGFICKMPKIIDPVTTHSSITTKADQRKMDPQPKGSSKAAGVVTVVLLIVIGAGVAAYFFYKKRHALHIPQEATFENTLYFNSNLSPGTSDTKDLMGNIEQNEHAII

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	GlyTouCan ID	Source
104	N-linked (GlcNAc...) asparagine	G24748EV	GlycoProtDB UniProt GlyGen
344	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen
529	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen
790			GlyGen
926	N-linked (GlcNAc...) asparagine		UniProt GlyGen
930	N-linked (GlcNAc...) asparagine		UniProt GlyGen
1159	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen
1204	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen