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MIRAGE
Fibroblast growth factor receptor 3

Summary
UniProt ID
Q61851
Gene Symbol
  • Fgfr3
  • Mfr3
  • Sam3
Organism
Mus musculus (house mouse)
GlyConnect
GlyGen
Q61851
PubChem
Q61851
Re-Glyco
Q61851
Annotation
Keyword
  • ATP-binding
  • Alternative splicing
  • Apoptosis
  • Cell membrane
  • Cytoplasmic vesicle
  • Disulfide bond
  • Endoplasmic reticulum
  • Glycoprotein
  • Immunoglobulin domain
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
  • Ubl conjugation
Gene Ontology (GO)
Displaying all 6 entries
GO Term
lysosome
plasma membrane
cytoplasmic vesicle
endoplasmic reticulum
perinuclear region of cytoplasm
cytoplasmic side of plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MVVPACVLVFCVAVVAGATSEPPGPEQRVVRRAAEVPGPEPSQQEQVAFGSGDTVELSCHPPGGAPTGPTVWAKDGTGLVASHRILVGPQRLQVLNASHEDAGVYSCQHRLTRRVLCHFSVRVTDAPSSGDDEDGEDVAEDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAILGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELMETDEAGSVYAGVLSYGVVFFLFILVVAAVILCRLRSPPKKGLGSPTVHKVSRFPLKRQVSLESNSSMNSNTPLVRIARLSSGEGPVLANVSELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIPVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSSGDDSVFTHDLLPPGPPSNGGPRT
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 9 entries
Position Description PubMed ID GlyTouCan ID Source
67
70
96 N-linked (GlcNAc...) asparagine
177
219 N-linked (GlcNAc...) asparagine
256 N-linked (GlcNAc...) asparagine
288 N-linked (GlcNAc...) asparagine
309 N-linked (GlcNAc...) asparagine
322 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 11 in total
Pathway Name Organism
FGFR3b ligand binding and activation Mus musculus
FGFR3c ligand binding and activation Mus musculus
FRS-mediated FGFR3 signaling Mus musculus
Negative regulation of FGFR3 signaling Mus musculus
PI-3K cascade:FGFR3 Mus musculus
PI3K Cascade Mus musculus
PI3K/AKT Signaling Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Mus musculus
Phospholipase C-mediated cascade; FGFR3 Mus musculus
RAF/MAP kinase cascade Mus musculus
Disease
Displaying all 5 entries
DO ID Disease Name Source
DOID:0060249 scoliosis
DOID:0060703 Muenke Syndrome
DOID:0080041 hypochondroplasia
DOID:13481 thanatophoric dysplasia
DOID:4480 achondroplasia
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025