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Semaphorin-3C

Summary

UniProt ID: Q62181
Gene Symbol: Sema3c SemE Semae
Gene ID: 20348
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0005580
Re-Glyco: Q62181

Annotation

Keyword: Developmental protein Differentiation Disulfide bond Glycoprotein Immunoglobulin domain Neurogenesis Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	Reference
neural crest cell migration	IMP	PMID
neural crest cell migration	IBA	GO_REF
somitogenesis	IEP	PMID
blood vessel remodeling	IMP	PMID
outflow tract septum morphogenesis	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

semaphorin-plexin signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

cardiac endothelial to mesenchymal transition

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification [inference]

somitogenesis

segmentation [inference]

somitogenesis

post-embryonic development

tissue remodeling [inference]

blood vessel remodeling

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

cardiac chamber morphogenesis [inference]

cardiac ventricle morphogenesis [inference]

cardiac right ventricle morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

dichotomous subdivision of an epithelial terminal unit [inference]

dichotomous subdivision of terminal units involved in salivary gland branching

cardiac septum morphogenesis [inference]

outflow tract septum morphogenesis

anatomical structure formation involved in morphogenesis [inference]

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

neural tube development

muscle tissue development [inference]

striated muscle tissue development [inference]

pulmonary myocardium development

tube development [inference]

neural tube development

animal organ development [inference]

heart development

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

cardiac endothelial to mesenchymal transition

locomotion [inference]

taxis [inference]

chemotaxis [inference]

negative chemotaxis

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [inference]

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

semaphorin-plexin signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [inference]

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

Displaying **all 3** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
plasma membrane	IBA	GO_REF
extracellular matrix	HDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

Displaying **all 5** entries
GO Term	Evidence Code	Reference
semaphorin receptor binding	IBA	GO_REF
semaphorin receptor binding	IPI	PMID
semaphorin receptor binding	IEA	GO_REF
neuropilin binding	IBA	GO_REF
chemorepellent activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

chemorepellent activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

chemorepellent activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAFRAICVLVGVFICSICVRGSSQPQARVYLTFDELRETKTSEYFSLSHQQLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEPLSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKERLTDNNRSTKQIHSMIARICPNDTGGQRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSASGELILEELEVFKNHVPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVRNNSTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQDSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWAGSVRALPFHPKDILGAFSHSEMQLINQYCKDTRQQQQLGEEPQKMRGDYGKLKALINSRKSRNRRNQLPES

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
81	N-linked (GlcNAc...) asparagine	UniProt
123	N-linked (GlcNAc...) asparagine	UniProt
252	N-linked (GlcNAc...) asparagine	UniProt
268	N-linked (GlcNAc...) asparagine	UniProt
465	N-linked (GlcNAc...) asparagine	UniProt
585	N-linked (GlcNAc...) asparagine	UniProt
586	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements