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Sorbin and SH3 domain-containing protein 1

Summary

UniProt ID: Q62417
Gene Symbol: Sorbs1 Kiaa1296 Sh3d5
Gene ID: 20411
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q62417
PubChem: Q62417
The O-GlcNAc Database: Q62417
RaftProt: Q62417
O-GlcNAcAtlas: Q62417
Re-Glyco: Q62417

Annotation

Keyword: Alternative splicing Cell junction Cell membrane Cytoskeleton Glycoprotein Nucleus Phosphoprotein Reference proteome Repeat SH3 domain Transport

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
insulin receptor signaling pathway	IDA	PMID
cell-substrate adhesion	IBA	GO_REF
cellular response to insulin stimulus	IMP	PMID
stress fiber assembly	IDA	PMID
positive regulation of glycogen biosynthetic process	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cellular component assembly [inference]

cell junction assembly [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

cell-substrate junction organization [inference]

cell-substrate junction assembly [inference]

focal adhesion assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to chemical [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of receptor clustering [inference]

regulation of skeletal muscle acetylcholine-gated channel clustering

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose import across plasma membrane

regulation of D-glucose import across plasma membrane [inference]

positive regulation of D-glucose import across plasma membrane

positive regulation of transmembrane transport [inference]

positive regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose import across plasma membrane

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose import across plasma membrane

regulation of cellular localization [inference]

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of receptor clustering [inference]

regulation of skeletal muscle acetylcholine-gated channel clustering

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of lipid biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of transmembrane transport [inference]

positive regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose import across plasma membrane

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose import across plasma membrane

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

regulation of cellular response to insulin stimulus [inference]

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of lipid biosynthetic process

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of lipid biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycogen metabolic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

regulation of glycogen metabolic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

regulation of small molecule metabolic process [inference]

regulation of glucose metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

regulation of glycogen metabolic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

regulation of lipid metabolic process [inference]

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process

regulation of transmembrane transport [inference]

regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose import across plasma membrane

regulation of D-glucose import across plasma membrane [inference]

positive regulation of D-glucose import across plasma membrane

positive regulation of transmembrane transport [inference]

positive regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose import across plasma membrane

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of lipid biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of glucose metabolic process [inference]

positive regulation of glycogen metabolic process [inference]

positive regulation of glycogen biosynthetic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of transmembrane transport [inference]

positive regulation of D-glucose transmembrane transport [inference]

positive regulation of D-glucose import across plasma membrane

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of cellular localization [inference]

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of receptor clustering [inference]

regulation of skeletal muscle acetylcholine-gated channel clustering

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of cellular response to insulin stimulus [inference]

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	Reference
stress fiber	IDA	PMID
nucleus	ISS	GO_REF
nucleus	ISO	GO_REF
nucleus	IDA	PMID
nucleus	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

flotillin complex

cellular anatomical structure [inference]

cytoplasm

microtubule organizing center [inference]

centrosome

cytosol

membrane

plasma membrane

membrane microdomain [inference]

membrane raft

nuclear matrix

cell junction [inference]

synapse

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

cell-substrate junction

focal adhesion

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

cytoskeleton

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
insulin receptor binding	ISO	GO_REF
insulin receptor binding	IDA	PMID
protein kinase binding	IDA	PMID
signaling receptor complex adaptor activity	ISO	GO_REF
signaling receptor complex adaptor activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

insulin receptor binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

signaling adaptor activity [inference]

signaling receptor complex adaptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSSECDVGSSKAVVNGLASGNHGPDKDMDPTKICTGKGTVTLRASSSYRGTPSSSPVSPQESPKHESKSGLEPEDPSADEWKLSSSADTNGNAQPSPLAAKGYRSVHPSLSADKPQGSPLLNEVSSSHIETDSQDFPPTSRPSSAYPSTTIVNPTIVLLQHNRDPASERRAGEQDPVPTPAELTSPGRASERRAKDASRRVVRSAQDLSDVSTDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDVHSPRYSFSDDTKSPLSVPRSKSEMNYIEGEKVVKRSATLPLPARSSSLKSSPERNDWEPLDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGRPTNLEKDLSFCQAELEADLEKVETVNKSPSANSPQSSAVSPTPDITSEPPGYIYSSNFHAVKRESDGTPGGLASLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKVDRKGGNAHMISSSSVHSRTFHTSNALGPGCKHKKPLSAAKACISEILPSKFKPRLSAPSALLQEQKSVLLPSEKAQSCENLCVSLNDSKRGLPLRVGGSIENLLMRSRRDYDSKSSSTMSLQEYGTSSRRPCPLSRKAGLHFSMFYRDMHQINRAGLSLGSISSSSVRDLASHFERSSLTLARGELGASQEGSEHIPKHTVSSRITAFEQLIQRSRSMPSLDFSGRLSKSPTPVLSRSGLTSARSAESLLESTKLRPREMDGMDSGGVYASPTCSNMADHALSFRSLVPSEPLSICSDELDHCSNVSNDSREGSGGSVHGDFPKHRLNKCKGTCPASYTRFTTIRKHEQQSSRQSDWRSDSRGDKNSLLRNIHLMSPLPFRLKKPLQQHPRQPPPSDSSESPAGQKADLPCHDPQDQPHSAGKPQVPTRLSSRHTMARLSHNSEPPLDRPAGLEDCTRAINNGNPVPYSDHGLDRNNNPQSELAAAHGDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGLEMRPARAKFDFKAQTLKELPLQKGDVVYIYRQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPRKLAPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVLKRPLVKTPVDYIDLPYSSSPSRSATVSPQQPQAQQRRVTPDRSQPSLDLCSYQALYSYVPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKPLYL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	PubMed ID	GlyTouCan ID	Source
51			GlyGen
105	16452088 22517741 22645316 26192747 30016717 35822049 36288343 40021952 40885482	G49108TO	The O-GlcNAc Database
179			GlyGen
409			GlyGen
563		G50282JC	GlyGen
593	16452088 22517741 22645316 26192747 30016717 35822049 36288343 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
597	16452088 22517741 22645316 26192747 30016717 35822049 36288343 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
1189	16452088 22517741 22645316 26192747 30016717 35822049 36288343 40021952 40885482	G49108TO	The O-GlcNAc Database
1199	16452088 22517741 22645316 26192747 30016717 35822049 36288343 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
1200	16452088 22517741 22645316 26192747 30016717 35822049 36288343 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database