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Acid-sensing ion channel 2

Summary

UniProt ID: Q62962
Gene Symbol: Accn1 Asic2 Bnac1
Gene ID: 25364
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: Q62962
PubChem: Q62962
Re-Glyco: Q62962

Annotation

Keyword: Alternative splicing Cell membrane Disulfide bond Glycoprotein Phosphoprotein Reference proteome Sodium channel Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	Reference
regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	ISO	GO_REF
monoatomic cation transport	ISO	GO_REF
sodium ion transport	ISO	GO_REF
sodium ion transport	IEA	GO_REF
phototransduction	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

phototransduction

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction

nervous system process [inference]

nervous system process involved in regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

sensory perception of sour taste

sensory perception of mechanical stimulus [inference]

sensory perception of sound

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

response to abiotic stimulus [inference]

response to pH [inference]

response to acidic pH

cellular response to acidic pH

cellular response to pH [inference]

cellular response to acidic pH

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

response to chemical [inference]

response to xenobiotic stimulus [inference]

cellular response to xenobiotic stimulus

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to cell junction [inference]

protein localization to synapse

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

sodium ion transport

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of ion transmembrane transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of cellular process [inference]

signal transduction [inference]

phototransduction

regulation of transmembrane transport [inference]

regulation of ion transmembrane transport

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of postsynapse organization [inference]

regulation of postsynapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of biological quality [inference]

regulation of membrane potential

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction

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GO Term	Evidence Code	Reference
plasma membrane	ISO	GO_REF
plasma membrane	EXP	PMID
plasma membrane	IDA	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

neuron spine [inference]

dendritic spine

cell body [inference]

neuronal cell body

postsynapse [inference]

dendritic spine

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GO Term	Evidence Code	Reference
ion channel activity	ISO	GO_REF
monoatomic ion channel activity	ISO	GO_REF
monoatomic ion channel activity	IDA	PMID
ion channel activity	IDA	PMID
monoatomic cation channel activity	ISO	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

pH-gated monoatomic ion channel activity [inference]

pH-gated sodium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

pH-gated monoatomic ion channel activity [inference]

pH-gated sodium channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

pH-gated sodium channel activity

pH-gated monoatomic ion channel activity [inference]

pH-gated sodium channel activity

monoatomic ion-gated channel activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDLKESPSEGSLQPSSIQIFANTSTLHGIRHIFVYGPLTIRRVLWAVAFVGSLGLLLVESSERVSYYFSYQHVTKVDEVVAQSLVFPAVTLCNLNGFRFSRLTTNDLYHAGELLALLDVNLQIPDPHLADPTVLEALRQKANFKHYKPKQFSMLEFLHRVGHDLKDMMLYCKFKGQECGHQDFTTVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASLLTILELFDYIYELIKEKLLDLLGKEEEEGSHDENMSTCDTMPNHSETISHTVNVPLQTALGTLEEIAC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
365	N-linked (GlcNAc...) asparagine	15504740		UniProt GlyGen
392	N-linked (GlcNAc...) asparagine	15504740		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Stimuli-sensing channels	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements