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Phosphatidylinositol 3-kinase regulatory subunit alpha

Summary

UniProt ID

Q63787

Gene Symbol

Pik3r1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q63787
PubChem: Q63787
The O-GlcNAc Database: Q63787

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Phosphoprotein
Protein transport
Reference proteome
Repeat
SH2 domain
SH3 domain
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of myoblast differentiation
negative regulation of osteoclast differentiation
negative regulation of proteolysis
positive regulation of smooth muscle cell proliferation
negative regulation of smooth muscle cell proliferation
response to glucocorticoid
positive regulation of synapse assembly
response to fatty acid
cellular response to fatty acid
regulation of protein localization to plasma membrane

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GO Term
nucleus
cytoplasm
cell-cell junction
membrane
protein-containing complex
cis-Golgi network
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA
perinuclear region of cytoplasm
perinuclear endoplasmic reticulum membrane

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GO Term
signaling receptor binding
insulin binding
kinase activator activity
protein kinase binding
ATPase binding
protein domain specific binding
nuclear estrogen receptor binding
ubiquitin protein ligase binding
ErbB-3 class receptor binding
insulin receptor substrate binding

Annotation information from UniProt.

Sequence

MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQPVLTLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDPPSVDLDVFDEHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQEVPSSEDYIQLLKKLIRSPNIPHQYWLTLQYLLKHFFKLSQASSKNLLNARALSEIFSHVLFRFPAASSDNTEHLIKAVELLISAEWSERQPAPALPPKPPKPTSIANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNDTIKIFEEQCHPQERYSKDYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVDDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Rattus norvegicus
CD28 dependent PI3K/Akt signaling	Rattus norvegicus
CDC42 GTPase cycle	Rattus norvegicus
Costimulation by the CD28 family	Rattus norvegicus
DAP12 signaling	Rattus norvegicus
Downstream TCR signaling	Rattus norvegicus
Downstream signal transduction	Rattus norvegicus
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Rattus norvegicus
Extra-nuclear estrogen signaling	Rattus norvegicus
FLT3 Signaling	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

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Annotation

International Collaboration

Acknowledgements