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Phosphatidylinositol 3-kinase regulatory subunit alpha

Summary

UniProt ID

Q63787

Gene Symbol

Pik3r1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q63787
PubChem: Q63787
The O-GlcNAc Database: Q63787

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Phosphoprotein
Protein transport
Reference proteome
Repeat
SH2 domain
SH3 domain
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
protein import into nucleus
extrinsic apoptotic signaling pathway via death domain receptors
intrinsic apoptotic signaling pathway in response to DNA damage
response to fructose
response to iron(II) ion
positive regulation of lamellipodium assembly
response to endoplasmic reticulum stress
regulation of toll-like receptor 4 signaling pathway
interleukin-18-mediated signaling pathway
positive regulation of protein import into nucleus

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GO Term
nucleus
cytoplasm
cell-cell junction
membrane
protein-containing complex
cis-Golgi network
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA
perinuclear region of cytoplasm
perinuclear endoplasmic reticulum membrane

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GO Term
protein heterodimerization activity
phosphoprotein binding
phosphotyrosine residue binding
1-phosphatidylinositol-3-kinase activity
insulin receptor binding
insulin-like growth factor receptor binding
platelet-derived growth factor receptor binding
neurotrophin TRKA receptor binding
calmodulin binding
protein phosphatase binding

Annotation information from UniProt.

Sequence

MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQPVLTLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDPPSVDLDVFDEHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQEVPSSEDYIQLLKKLIRSPNIPHQYWLTLQYLLKHFFKLSQASSKNLLNARALSEIFSHVLFRFPAASSDNTEHLIKAVELLISAEWSERQPAPALPPKPPKPTSIANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNDTIKIFEEQCHPQERYSKDYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVDDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 20** of 53 in total

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Pathway Name	Organism
G alpha (q) signalling events	Rattus norvegicus
GAB1 signalosome	Rattus norvegicus
GP1b-IX-V activation signalling	Rattus norvegicus
GPVI-mediated activation cascade	Rattus norvegicus
IRS-mediated signalling	Rattus norvegicus
Interleukin receptor SHC signaling	Rattus norvegicus
Interleukin-3, Interleukin-5 and GM-CSF signaling	Rattus norvegicus
Interleukin-7 signaling	Rattus norvegicus
MET activates PI3K/AKT signaling	Rattus norvegicus
PI-3K cascade:FGFR1	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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External Links

Annotation

International Collaboration

Acknowledgements