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UDP-glucuronosyltransferase 1A1

Summary

UniProt ID: Q63886
Gene Symbol: Ugt1 Ugt1a1
Gene ID: 394436
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0005608
GlyGen: Q63886
PubChem: Q63886
Re-Glyco: Q63886

Annotation

Keyword: Alternative splicing Endoplasmic reticulum Glycoprotein Glycosyltransferase Lipid metabolism Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
cell activation	IMP	PMID
liver development	IMP	PMID
liver development	IBA	GO_REF
bilirubin conjugation	ISO	GO_REF
bilirubin conjugation	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell activation

fibroblast activation [inference]

hepatic stellate cell activation

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

canonical NF-kappaB signal transduction

metabolic process [inference]

xenobiotic metabolic process

xenobiotic catabolic process [inference]

biphenyl catabolic process

catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

xenobiotic catabolic process [inference]

biphenyl catabolic process

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

flavonoid metabolic process

flavone metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

heme metabolic process [inference]

heme catabolic process

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

pigment metabolic process [inference]

heme metabolic process [inference]

heme catabolic process

pigment catabolic process [inference]

heme catabolic process

flavone metabolic process

hormone metabolic process [inference]

estrogen metabolic process

benzene-containing compound metabolic process [inference]

biphenyl metabolic process [inference]

biphenyl catabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

estrogen metabolic process

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

multicellular organismal process [inference]

cell activation

fibroblast activation [inference]

hepatic stellate cell activation

tissue remodeling [inference]

connective tissue replacement

developmental process [inference]

anatomical structure development [inference]

tube development [inference]

digestive tract development

animal organ development [inference]

gland development [inference]

liver development

pigmentation [inference]

pigment accumulation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

cellular response to stress [inference]

cellular response to DNA damage stimulus

response to external stimulus [inference]

pigment accumulation

response to chemical [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

canonical NF-kappaB signal transduction

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

estrogen metabolic process

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GO Term	Evidence Code	Reference
endoplasmic reticulum	ISO	GO_REF GO_REF
endoplasmic reticulum	IBA	GO_REF
endoplasmic reticulum	IEA	GO_REF
endoplasmic reticulum lumen	IDA	PMID PMID
endoplasmic reticulum membrane	ISS	GO_REF

GO Hierarchy

cellular component

protein-containing complex

endoplasmic reticulum protein-containing complex [inference]

endoplasmic reticulum chaperone complex

catalytic complex [inference]

cytochrome complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

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GO Term	Evidence Code	Reference
retinoic acid binding	ISO	GO_REF
retinoic acid binding	IEA	GO_REF
enzyme inhibitor activity	ISO	GO_REF
enzyme inhibitor activity	IBA	GO_REF
enzyme inhibitor activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding [inference]

enzyme binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

steroid binding

isoprenoid binding [inference]

retinoid binding [inference]

retinoic acid binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTVVCWSSRLLLLLPYLLLCVFGPSASHAGRLLVFPMDGSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYTLRKFPVPFQKENVTATLVELGRTAFNQDSFLLRVVKIYMKVKRDSSMLLAGCSHLLHNAEFMASLEESHFDALLTDPFLPCGSIVAQYLTVPTVYFLNKLPCSLDSEATQCPVPLSYVPKSLSFNSDRMNFLQRVKNVLLAVSENFMCRVVYSPYGSLATEILQKEVTVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	GlyTouCan ID	Source
89	N-linked (GlcNAc...) asparagine	G62765YT	GlycoProtDB UniProt GlyGen
297	N-linked (GlcNAc...) asparagine	G02815KT	UniProt GlyGen
435	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen