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5'-3' exonuclease PLD3

Summary

UniProt ID

Q640B3

Gene Symbol

pld3

Gene ID

496432

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

Re-Glyco: Q640B3

Annotation

Keyword: Endoplasmic reticulum Endosome Exonuclease Glycoprotein Golgi apparatus Immunity Inflammatory response Lysosome Reference proteome Repeat Signal-anchor Transmembrane helix Ubl conjugation

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
immune system process
inflammatory response
myotube differentiation
regulation of cytokine production involved in inflammatory response

GO Hierarchy

biological process

immune system process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

myotube differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

myotube differentiation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
Golgi membrane	ISS	GO_REF
Golgi membrane	IEA	GO_REF
endoplasmic reticulum membrane	ISS	GO_REF
endoplasmic reticulum membrane	IEA	GO_REF
endomembrane system	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

endomembrane system

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

endosome membrane [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

Displaying 1 entry
GO Term	Evidence Code	Reference
single-stranded DNA 5'-3' DNA exonuclease activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' exonuclease activity [inference]

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

catalytic activity, acting on a nucleic acid [inference]

nuclease activity [inference]

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' exonuclease activity [inference]

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

DNA nuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MNPKVEYKQIQSHDEAENQVLQHECHQAKARKYYRCAVVIAIIITLLFCVLASQLLLFPLFSITSQTTTEIVLNKDIQCDDQCRFVLVESIPEGLVYDANATINPSIFQSWLNILTSAKSSVDIASFYWTLTNEDTQTQEPSAHQGELILQELLNLKQRGVSVRVAVNPPDSPLRAKDISALKDSGADVRVVDLPKLTDGVLHTKFWVVDSEHFYIGSANMDWRSLTQVKELGATIYNCSCLAEDLKKIFEAYWILGLPNATLPSPWPVNYSTPYNKDTPMQVMLNSTASQVYISSSPPPLSATGRTDDLQSIINIIDDAKKFVYISVMDYSPTEEFSHPRRYWPYIDNHLRKAVYERNVNVRLLISCWQNSRPSMFTFLRSLAALHSNKSHYNIEVKIFVVPATEVQKKIPYARVNHNKYMVTDRVAYIGTSNWSGDYFIHTAGSALIVNQTQSVGTSDTIQMQLQAVFERDWNSNYSRTFNTLSSWKEKCIF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	Source
100	N-linked (GlcNAc...) asparagine	UniProt
238	N-linked (GlcNAc...) asparagine	UniProt
260	N-linked (GlcNAc...) asparagine	UniProt
270	N-linked (GlcNAc...) asparagine	UniProt
286	N-linked (GlcNAc...) asparagine	UniProt
389	N-linked (GlcNAc...) asparagine	UniProt
434	N-linked (GlcNAc...) asparagine	UniProt
451	N-linked (GlcNAc...) asparagine	UniProt
477	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Role of phospholipids in phagocytosis	Xenopus tropicalis

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements