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Wings apart-like protein homolog

Summary

UniProt ID: Q65Z40
Gene Symbol: Kiaa0261 Wapal Wapl
Gene ID: 218914
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q65Z40
PubChem: Q65Z40
The O-GlcNAc Database: Q65Z40
O-GlcNAcAtlas: Q65Z40
Re-Glyco: Q65Z40

Annotation

Keyword: Acetylation Chromosome Coiled coil Cytoplasm Mitosis Nucleus Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	Reference
mitotic sister chromatid segregation	ISS	GO_REF
mitotic sister chromatid segregation	ISO	GO_REF
mitotic sister chromatid segregation	IEA	GO_REF
mitotic cell cycle	IMP	PMID
mitotic cell cycle	IGI	PMID

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

cell cycle [inference]

mitotic cell cycle

cell cycle process [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

chromosome segregation [inference]

nuclear chromosome segregation [inference]

sister chromatid segregation [inference]

mitotic sister chromatid segregation

attachment of spindle microtubules to kinetochore

chromosome separation [inference]

meiotic chromosome separation

meiotic cell cycle process [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

meiotic chromosome separation

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

mitotic cell cycle process [inference]

mitotic sister chromatid segregation

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin looping

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

chromosome organization [inference]

sister chromatid segregation [inference]

mitotic sister chromatid segregation

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

organelle assembly [inference]

membraneless organelle assembly [inference]

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

cellular component assembly [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

spindle assembly [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

reproductive process [inference]

meiotic cell cycle process [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis

meiotic chromosome separation

chromosome organization involved in meiotic cell cycle [inference]

homologous chromosome pairing at meiosis

response to stimulus [inference]

response to chemical [inference]

response to toxic substance

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromatin

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of sister chromatid cohesion

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

negative regulation of DNA replication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of protein metabolic process [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

negative regulation of DNA replication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

regulation of protein metabolic process [inference]

regulation of translation [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

regulation of fibroblast proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation

positive regulation of protein metabolic process [inference]

positive regulation of translation

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of sister chromatid cohesion

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion

regulation of chromosome organization [inference]

regulation of sister chromatid cohesion [inference]

negative regulation of sister chromatid cohesion

regulation of chromosome condensation

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of sister chromatid cohesion [inference]

negative regulation of sister chromatid cohesion

negative regulation of cell cycle process [inference]

negative regulation of sister chromatid cohesion

regulation of chromosome segregation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of sister chromatid cohesion

regulation of meiotic cell cycle

regulation of reproductive process [inference]

regulation of meiotic cell cycle

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of binding [inference]

negative regulation of chromatin binding

regulation of binding [inference]

negative regulation of binding [inference]

negative regulation of chromatin binding

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	Reference
kinetochore	IDA	PMID
chromatin	ISS	GO_REF
chromatin	ISO	GO_REF
chromatin	IDA	PMID
chromatin	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

female germ cell nucleus [inference]

germinal vesicle

membraneless organelle [inference]

intracellular membraneless organelle [inference]

spindle [inference]

mitotic spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

female germ cell nucleus [inference]

germinal vesicle

intracellular membraneless organelle [inference]

spindle [inference]

mitotic spindle

intercellular bridge

supramolecular complex [inference]

kinetochore

synaptonemal structure [inference]

synaptonemal complex

Displaying **all 3** entries
GO Term	Evidence Code	Reference
ATP-dependent protein-DNA unloader activity	ISS	GO_REF
ATP-dependent protein-DNA unloader activity	ISO	GO_REF
ATP-dependent protein-DNA unloader activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA [inference]

ATP-dependent protein-DNA unloader activity

ATP-dependent activity [inference]

ATP-dependent activity, acting on DNA [inference]

ATP-dependent protein-DNA unloader activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEIPKKPKVEEEDTGDPFGFDSDDESLPVSSKNLAQGKGSSYSESSEAAQLEEVTSVFEANSKCSHVVGEDSFASDRCLLVEDTLIGKEKSISRIPEDNANKSSCTKLLTSDKVENFSEEHEKNSHHFHKNAEDSTKKPNAETAVASEYKADETKETNDTWNSQSGKRTESPSESCPVKGSVRTGLYEWDNDFEDIRSEDCILSLDNESLLEMKDEDLKNRIGGLENLNETFEEDIIQSVLRPSNCRTYCRANKARSSQGASNFDKLMDGTSQSLAKANSESSKDGLNQAKKGSASCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHDETGGDEGGSGSSNYKIKYFGFDDLSESEDDDDDDCQVERKKDKKRTKTAPSPSQQPPPESSDNSQDSQSSTNNAENLDFTEDLPGVPESVKKPISKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPIAKPQRVTVRLSSKEPNQKDDGVFKAPAPPLKVIKTVTIPTQPYQEIVTALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVHNKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRDDEDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIISSAKALQHCEDLIQQYNRAENSICVADSNPLPYQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQEGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMQTSCSFDSSFSSGEGDHSLRLAGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGAEEKQKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
424		30059200	G49108TO	GlyGen The O-GlcNAc Database
426		30059200	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cohesin Loading onto Chromatin	Mus musculus
Establishment of Sister Chromatid Cohesion	Mus musculus
Resolution of Sister Chromatid Cohesion	Mus musculus
Separation of Sister Chromatids	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements