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Calcitonin gene-related peptide type 1 receptor

Summary

UniProt ID: Q68EK2
Gene Symbol: calcrl calcrla si:dkey-249o24.2 zgc:100872
Gene ID: 445508
Organism: Danio rerio (zebrafish)

External Links

PubChem: Q68EK2
Re-Glyco: Q68EK2

Annotation

Keyword: Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	Reference
angiogenesis	IBA	GO_REF
somitogenesis
cell surface receptor signaling pathway	IEA	GO_REF
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	GO_REF
artery morphogenesis

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification [inference]

somitogenesis

segmentation [inference]

somitogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis

anatomical structure formation involved in morphogenesis [inference]

homeostatic process [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic anion homeostasis [inference]

chloride ion homeostasis

inorganic ion homeostasis [inference]

chloride ion homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Displaying **all 3** entries
GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
adrenomedullin receptor activity	IBA	GO_REF
calcitonin gene-related peptide receptor activity	IBA	GO_REF
calcitonin receptor activity	IEA	GO_REF

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

calcitonin family receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

calcitonin family receptor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTASCWTICLFLLGSVTEFIVLASPEVNESQQQHPQNVYHDIGVTRNKIVTAQFECYQKIMKDNSQDRRGPVCNRTWDGWLCWDDTEAGITSEQHCPDYFQDFDPTEMVTKICTESGQWFLHPESNRTWTNFTRCNLHTTEGRRTAMNLFYLALIGHGLSLTSLFISLGIFFHFKSLSCQRITLHKNLFFSFVLNSIITIIWLTAVANNQELVQQNPISCKISQFIHLYIFGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYLLGWGFPLIPATIHAVARSYYYNDNCWISSNTSLLYIIHGPICAAMLVNLFFLLNIVRVLITKLKVTHQAKSSLYMKAVRATLILVPLLGIQYVLLPYKPSGRVSAEIYDYIMHILMHYQGLLVATIFCFFNGEVQAVLRRHWNQYRIQFGSTITQSDALRSASYTASSITEVQGCYSIDGHTEHLNGKNYHDFDNAIIKPENPFA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
28	N-linked (GlcNAc...) asparagine	UniProt
74	N-linked (GlcNAc...) asparagine	UniProt
126	N-linked (GlcNAc...) asparagine	UniProt
131	N-linked (GlcNAc...) asparagine	UniProt
295	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Calcitonin-like ligand receptors	Danio rerio
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	Danio rerio

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UniCarb-DR

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