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ATPase MORC2A

Summary

UniProt ID: Q69ZX6
Gene Symbol: Kiaa0852 Morc2a Zcwcc1
Gene ID: 74522
Organism: Mus musculus (house mouse)

External Links

PubChem: Q69ZX6
The O-GlcNAc Database: Q69ZX6
Re-Glyco: Q69ZX6

Annotation

Keyword: ATP-binding Acetylation Chromosome Coiled coil Cytoplasm Hydrolase Isopeptide bond Magnesium Nucleus Phosphoprotein Reference proteome Ubl conjugation Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
chromatin remodeling	ISS	GO_REF
chromatin remodeling	ISO	GO_REF
cellular response to DNA damage stimulus	ISS	GO_REF
DNA damage response	ISS	GO_REF
DNA damage response	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

heterochromatin organization [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

cellular component assembly [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation

transposable element silencing by heterochromatin formation

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
heterochromatin	ISS	GO_REF
heterochromatin	ISO	GO_REF
nucleus	ISS	GO_REF
nucleus	ISO	GO_REF
nucleus	EXP	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

chromatin [inference]

heterochromatin

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	Reference
magnesium ion binding	ISS	GO_REF
magnesium ion binding	ISO	GO_REF
chromatin binding	ISS	GO_REF
chromatin binding	ISO	GO_REF
ATP binding	ISS	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA [inference]

ATP-dependent chromatin remodeler activity

binding [inference]

chromatin binding

protein binding [inference]

histone binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

transition metal ion binding [inference]

zinc ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

ATP-dependent activity, acting on DNA [inference]

ATP-dependent chromatin remodeler activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAFTNYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPITDNVEKFAIETELVYKYSPFHTEEQVMNQFMKIPGNSGTLVIIFNLKLMDNGEPELDIISNPKDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRMGGDLTRDSRVMLRQVQNTAITLRREADVKKRIKDAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRFKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVETDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTLKKDPKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPIEEPVRRPQRPRSPPLPAVIKNAPSRPPSIQTPRPSTQLRKTSVISLPKPPTTAARGETSTSRLLQPTEAPRKPANPPIKTVPRPTPPVHTPPLSLIPSSKSLREVPAQKAIKTPVVKKPEPPVKQSVATSGRKRSLAVSDEEEAEEEAEKRRERCKRGKLAVKEEKKEANELSDSAGEDHPAELRKAQKDKGLHVEVRVNREWYTGRVTAVEVGKNAVRWKVKFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSPDTQQEGGEEEEAMVARQAVALPEPSTSDGLPIEPDTTATSPSHETIDLLVQILRNCLRYFLPPSFPISKKELSVMNSEELISFPLKEYFKQYEVGLQNLCHSYQSRADSRAKASEESLRTSEKKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites