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Endothelial cell-selective adhesion molecule

Summary

UniProt ID: Q6AYD4
Gene Symbol: Esam
Gene ID: 300519
Organism: Rattus norvegicus (Norway rat)

External Links

Re-Glyco: Q6AYD4

Annotation

Keyword: Cell adhesion Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Intellectual disability Phosphoprotein Reference proteome Repeat Signal Tight junction Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
homophilic cell-cell adhesion	ISO	GO_REF
homophilic cell-cell adhesion	IBA	GO_REF
protein localization	ISO	GO_REF
intracellular protein localization	ISO	GO_REF
regulation of actin filament polymerization	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

homophilic cell-cell adhesion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

tight junction organization [inference]

tight junction assembly [inference]

bicellular tight junction assembly

localization [inference]

macromolecule localization [inference]

intracellular protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

regulation of protein polymerization [inference]

regulation of actin filament polymerization

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of protein-containing complex assembly [inference]

regulation of protein polymerization [inference]

regulation of actin filament polymerization

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
cell-cell junction	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

adherens junction

tight junction [inference]

bicellular tight junction

Displaying **all 2** entries
GO Term	Evidence Code	Reference
cell-cell adhesion mediator activity	ISO	GO_REF
cell-cell adhesion mediator activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MILPARTPETSLLRVLFLGLSTLAAFSLAQMELHVPPGLNKLEAVEGEEVVLPAWYTMAREESSSHPWEAPFLIWFLEQEGKEPKQVLSYFKGSLSNKPGVTLVHSISTRNVSLRLDALQEGDSGTYRCSVNAYDSDGKNIGHSIKTIELKVLVPPAPPSCSFQGVPYVGTNVTLNCKSPRSKPTAQYQWERLAPSSQVFFGPALDTVRGSLKLTNISTAMSGVYVCKAQNRVGFAQCNVTLDVMTGSKAAVVAGAVVGTFVGLVLIAGLVLLYQRRSKTLEELANDIKEDAIAPRTLPWTKGSDTISKNGTLSSVTSARALRPPKAAPPRPGTFTPTPSVSSQALSSPRLPRTDGPPPQAVSLTPGGVSSSTLNRMGAVPVMVPAQSQAGSLV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
111	N-linked (GlcNAc...) asparagine	UniProt
172	N-linked (GlcNAc...) asparagine	UniProt
216	N-linked (GlcNAc...) asparagine	UniProt
239	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Cell surface interactions at the vascular wall	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements