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MIRAGE
von Willebrand factor A domain-containing protein 1

Summary
UniProt ID
Q6PCB0
Gene Symbol
  • VWA1
Gene ID
64856
Organism
Homo sapiens (human)
GlyGen
Q6PCB0
Re-Glyco
Q6PCB0
Annotation
Keyword
  • Alternative splicing
  • Basement membrane
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Neuropathy
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Signal
Gene Ontology (GO)
Displaying all 6 entries
GO Term
endoplasmic reticulum lumen
extracellular exosome
interstitial matrix
basement membrane
extracellular space
collagen-containing extracellular matrix
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
microfibril binding
protein homodimerization activity
Annotation information from UniProt.
Sequence
MLPWTALGLALSLRLALARSGAERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPTPGTASREP
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 12 in total
Position Description PubMed ID GlyTouCan ID Source
84
264 N-linked (GlcNAc...) asparagine
315
322
351
358
386
402
404
435
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Post-translational protein phosphorylation Homo sapiens
Regulation of IGF Activity by IGFBP Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0081426 autosomal recessive distal hereditary motor neuronopathy 7
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025