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von Willebrand factor A domain-containing protein 1

Summary

UniProt ID: Q6PCB0
Gene Symbol: VWA1
Gene ID: 64856
Organism: Homo sapiens (human)

External Links

GlyGen: Q6PCB0
Re-Glyco: Q6PCB0

Annotation

Keyword: Alternative splicing Basement membrane Disease variant Disulfide bond Glycoprotein Neuropathy Phosphoprotein Proteomics identification Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
extracellular matrix organization
behavioral response to pain
protein homooligomerization

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

extracellular structure organization [inference]

extracellular matrix organization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

external encapsulating structure organization [inference]

extracellular matrix organization

multicellular organismal process [inference]

behavior [inference]

behavioral response to pain

multicellular organismal response to stress [inference]

response to pain [inference]

behavioral response to pain

response to stimulus [inference]

response to stress [inference]

multicellular organismal response to stress [inference]

response to pain [inference]

behavioral response to pain

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
basement membrane	IEA	GO_REF GO_REF
interstitial matrix	IEA	GO_REF
obsolete extracellular space
endoplasmic reticulum lumen	TAS	Reactome
extracellular matrix	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

external encapsulating structure [inference]

extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	Reference
protein homodimerization activity	IEA	GO_REF
microfibril binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

extracellular matrix binding [inference]

microfibril binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLPWTALGLALSLRLALARSGAERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPTPGTASREP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
84		30459171	G43417UB	GlyGen
264	N-linked (GlcNAc...) asparagine			UniProt GlyGen
315		25813380	G57321FI	GlyGen
322		25813380 30459171	G43417UB G29068FM G57321FI	GlyGen
351		25813380	G57321FI	GlyGen
358		25813380	G57321FI	GlyGen
386		37074911	G56518TU G01160VV G49589RB G35541EV G40206WX G40834TG G45395BF G59324HL G31028YV G40574BA G08918WF G00912UN G87661QW G46691LC G04657PL G27058EU G41071NU G72747WU G70619PT G59626AS G42124LM G90659AW G62765YT G10486CT	GlyGen
402		25813380	G57321FI	GlyGen
404		25813380	G57321FI	GlyGen
435		23584533	G57321FI	GlyGen