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MIRAGE
Poly [ADP-ribose] polymerase tankyrase-1
Summary
- UniProt ID
- Q6PFX9
- Gene Symbol
- Tnks Tnks1
- Gene ID
- 21951
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- 3D-structure ADP-ribosylation ANK repeat Alternative splicing Cytoskeleton Glycosyltransferase Golgi apparatus Membrane Metal-binding Mitosis NAD Nuclear pore complex Nucleotidyltransferase Phosphoprotein Reference proteome Repeat Telomere Ubl conjugation Wnt signaling pathway Zinc
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein polyubiquitination | ||
| protein polyubiquitination | ||
| protein polyubiquitination | ||
| protein transport |
|
|
| Wnt signaling pathway |
|
|
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of organelle organization [inference]
negative regulation of cellular component organization [inference]
regulation of cell cycle [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| Golgi membrane | ||
| Golgi membrane | ||
| Golgi membrane | ||
| chromosome, telomeric region | ||
| chromosome, telomeric region |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| NAD+ poly-ADP-ribosyltransferase activity | ||
| NAD+ poly-ADP-ribosyltransferase activity | ||
| NAD+ poly-ADP-ribosyltransferase activity | ||
| NAD+ poly-ADP-ribosyltransferase activity | ||
| zinc ion binding |
GO Hierarchy
Sequence
MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGPTPASPTAGGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGAVCTVAAPAAVPAASAAVGVAPTPAGGGGGGGNNSASSASSPTSSSSSSPSSPGSSLAESPEAAGVGSTATLGAGAAGLGPGVPAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPMRTSDVDYRLLEASKAGDLETVKQLCSPQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFKPQATVVSASLISPASTPSCLSAASSIDNLTGPLTDLAVGGASNAGDGAAGAERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQKT
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Degradation of AXIN | Mus musculus |
| Regulation of PTEN stability and activity | Mus musculus |
| TCF dependent signaling in response to WNT | Mus musculus |
| Ub-specific processing proteases | Mus musculus |
