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MIRAGE
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
Summary
- UniProt ID
- Q6R0H7
- Gene Symbol
- Gnas Gnas1
- Gene ID
- 14683
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- ADP-ribosylation Alternative splicing Cell membrane Coiled coil GTP-binding Hydrolase Magnesium Metal-binding Phosphoprotein Reference proteome Transducer
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| skeletal system development | ||
| tissue homeostasis | ||
| endochondral ossification | ||
| energy reserve metabolic process | ||
| regulation of transcription by RNA polymerase II |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| G-protein alpha-subunit binding | ||
| GTPase activity | ||
| GTPase activity | ||
| GTPase activity | ||
| GTPase activity |
Sequence
MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQRAAQRRSFLNAHHRSAAAAAAAQVLPESSESESDHEHEEVEPELARPECLEYDQDDYETETDSETEPESDIESETEIETEPETEPETAPTTEPETEPEDERGPRGATFNQSLTQRLHALKLQSADASPRRAQPTTQEPESASEGEEPQRGPLDQDPRDPEEEPEERKEENRQPRRCKTRRPARRRDQSPESPPRKGPIPIRRH
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (s) signalling events | Mus musculus |
| GPER1 signaling | Mus musculus |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | Mus musculus |
| Glucagon-type ligand receptors | Mus musculus |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | Mus musculus |
| Prostacyclin signalling through prostacyclin receptor | Mus musculus |
| Vasopressin regulates renal water homeostasis via Aquaporins | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080053 | pseudohypoparathyroidism type 1A | |
| DOID:4184 | pseudohypoparathyroidism | |
| DOID:4183 | pseudopseudohypoparathyroidism | |
| DOID:5419 | schizophrenia |
