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Netrin receptor UNC5A
Summary
- UniProt ID
- Q6ZN44
- Gene Symbol
- KIAA1976 UNC5A UNC5H1
- Gene ID
- 90249
- Organism
- Homo sapiens (human)
Annotation
- Keyword
- 3D-structure Alternative splicing Apoptosis Cell membrane Cell projection Developmental protein Disulfide bond Glycoprotein Immunoglobulin domain Phosphoprotein Proteomics identification Receptor Reference proteome Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| apoptotic process |
|
|
| neuron projection development | ||
| anterior/posterior axon guidance | ||
| netrin-activated signaling pathway | ||
| netrin-activated signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| neuron projection membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| netrin receptor activity | ||
| netrin receptor activity |
Sequence
MAVRPGLWPALLGIVLAAWLRGSGAQQSATVANPVPGANPDLLPHFLVEPEDVYIVKNKPVLLVCKAVPATQIFFKCNGEWVRQVDHVIERSTDGSSGLPTMEVRINVSRQQVEKVFGLEEYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSASAAVIVYVDGSWSPWSKWSACGLDCTHWRSRECSDPAPRNGGEECQGTDLDTRNCTSDLCVHTASGPEDVALYVGLIAVAVCLVLLLLVLILVYCRKKEGLDSDVADSSILTSGFQPVSIKPSKADNPHLLTIQPDLSTTTTTYQGSLCPRQDGPSPKFQLTNGHLLSPLGGGRHTLHHSSPTSEAEEFVSRLSTQNYFRSLPRGTSNMTYGTFNFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYLTLHKPEDVRLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPDSWSLRLKKQSCEGSWEDVLHLGEEAPSHLYYCQLEASACYVFTEQLGRFALVGEALSVAAAKRLKLLLFAPVACTSLEYNIRVYCLHDTHDALKEVVQLEKQLGGQLIQEPRVLHFKDSYHNLRLSIHDVPSSLWKSKLLVSYQEIPFYHIWNGTQRYLHCTFTLERVSPSTSDLACKLWVWQVEGDGQSFSINFNITKDTRFAELLALESEAGVPALVGPSAFKIPFLIRQKIISSLDPPCRRGADWRTLAQKLHLDSHLSFFASKPSPTAMILNLWEARHFPNGNLSQLAAAVAGLGQPDAGLFTVSEAEC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 107 |
|
|
||
| 218 |
|
|
||
| 245 |
|
|
||
| 248 |
|
|
||
| 251 |
|
|
||
| 287 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ligand-independent caspase activation via DCC | Homo sapiens |
| Netrin mediated repulsion signals | Homo sapiens |
| Netrin-1 signaling | Homo sapiens |
