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Envelope glycoprotein gp160

Summary

UniProt ID: Q70626
Gene Symbol: env
Gene ID
Organism: Human immunodeficiency virus type 1 lw12.3 isolate

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Surface protein gp120

Re-Glyco

Q70626

Annotation

Keyword: 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Glycoprotein Host cell membrane Host endosome Palmitate Signal Transmembrane helix Viral attachment to host cell Viral envelope protein Viral immunoevasion

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
virion attachment to host cell	ISS	GO_REF
virion attachment to host cell	IEA	GO_REF GO_REF
fusion of virus membrane with host plasma membrane	ISS	GO_REF
fusion of virus membrane with host plasma membrane	IEA	GO_REF
viral protein processing	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

clathrin-dependent endocytosis [inference]

clathrin-dependent endocytosis of virus by host cell

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

membrane fusion [inference]

fusion of virus membrane with host plasma membrane

viral process [inference]

viral protein processing

membrane fusion involved in viral entry into host cell [inference]

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

symbiont-mediated perturbation of host process [inference]

symbiont-mediated perturbation of host defense response

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

symbiont-mediated perturbation of host process [inference]

symbiont-mediated perturbation of host defense response

adhesion of symbiont to host [inference]

adhesion of symbiont to host cell [inference]

virion attachment to host cell

symbiont entry into host [inference]

symbiont entry into host cell [inference]

endocytosis involved in viral entry into host cell [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

clathrin-dependent endocytosis [inference]

clathrin-dependent endocytosis of virus by host cell

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis of virus by host cell [inference]

clathrin-dependent endocytosis of virus by host cell

clathrin-dependent endocytosis [inference]

clathrin-dependent endocytosis of virus by host cell

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of protein localization to membrane [inference]

regulation of receptor clustering [inference]

positive regulation of receptor clustering

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of cellular localization [inference]

regulation of plasma membrane raft polarization [inference]

positive regulation of plasma membrane raft polarization

regulation of protein localization to membrane [inference]

regulation of receptor clustering [inference]

positive regulation of receptor clustering

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of plasma membrane raft polarization

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of plasma membrane raft polarization

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

regulation of cellular component organization [inference]

positive regulation of cellular component organization [inference]

positive regulation of plasma membrane raft polarization

regulation of plasma membrane organization [inference]

regulation of plasma membrane raft polarization [inference]

positive regulation of plasma membrane raft polarization

regulation of cellular localization [inference]

regulation of plasma membrane raft polarization [inference]

positive regulation of plasma membrane raft polarization

regulation of protein localization to membrane [inference]

regulation of receptor clustering [inference]

positive regulation of receptor clustering

positive regulation of protein localization to membrane [inference]

positive regulation of receptor clustering

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
membrane	IEA	GO_REF
viral envelope	IEA	GO_REF GO_REF
host cell plasma membrane	ISS	GO_REF
host cell plasma membrane	IEA	GO_REF GO_REF
host cell endosome membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

virion component [inference]

viral membrane [inference]

viral envelope

virion membrane

cellular anatomical structure [inference]

membrane

other organism part [inference]

host cellular component [inference]

host cell part [inference]

host cell membrane [inference]

Displaying 1 entry
GO Term	Evidence Code	Reference
structural molecule activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

structural molecule activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRVKEKYQHLRRWGWRWGTMLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLKNDTNTNSSSGGMIMEKGEIKNCSFNISTSIRGKVQKEYAFFYKHDIIPIDNDTTSYTLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVVIRSANLTDNVKTIIVQLNQSVEINCTRPNNNTRKRIRIQRGPGRTFVTIGKIGNMRQAHCNISRAKWNNTLKQIASKLREQYGNNKTIIFKQSSGGDLEIVTHSFNCGGEFFYCNSTQLFNSTWFNSTWSTEGSNNTEGSDTITLPCRIKQIINMWQEVGKAMYAPPISGQIRCSSNITGLLLTRDGGNNNNGSEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGALFLGFLGAAGSTMGAASMTLTVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKLICTTAVPWNASWSNKSLEQIWNHTTWMEWDREINNYTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWFNITNWLWYIKIFIMIVGGLVGLRIVFAVLSIVNRVRQGHSPLSFQTHLPTPGGPDRPEGIEEEGGERDRDRSIRLVNGSLALIWDDLRSLCLFSYHRLRDLLLIVTRIVELLGRRGWEALKYWWNLLQYWSQELKNSAVSLLNATAIAVAEGTDRVIEVVQGACRAIRHIPRRIRQGLERILL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 30 in total

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Position	Description	Source
88	N-linked (GlcNAc...) asparagine; by host	UniProt
136	N-linked (GlcNAc...) asparagine; by host	UniProt
141	N-linked (GlcNAc...) asparagine; by host	UniProt
156	N-linked (GlcNAc...) asparagine; by host	UniProt
160	N-linked (GlcNAc...) asparagine; by host	UniProt
186	N-linked (GlcNAc...) asparagine; by host	UniProt
197	N-linked (GlcNAc...) asparagine; by host	UniProt
230	N-linked (GlcNAc...) asparagine; by host	UniProt
234	N-linked (GlcNAc...) asparagine; by host	UniProt
241	N-linked (GlcNAc...) asparagine; by host	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Dectin-2 family	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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