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Ciliary neurotrophic factor receptor subunit alpha

Summary

UniProt ID: Q71DR4
Gene Symbol: CNTFR
Gene ID: 442941
Organism: Canis lupus familiaris (dog)

External Links

Re-Glyco: Q71DR4

Annotation

Keyword: Cell membrane Disulfide bond GPI-anchor Immunoglobulin domain Receptor Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
positive regulation of cell population proliferation	IBA	GO_REF
positive regulation of cell population proliferation	IEA	GO_REF
ciliary neurotrophic factor-mediated signaling pathway	IBA	GO_REF
ciliary neurotrophic factor-mediated signaling pathway	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

ciliary neurotrophic factor-mediated signaling pathway

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

ciliary neurotrophic factor-mediated signaling pathway

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
external side of plasma membrane	ISS	GO_REF
external side of plasma membrane	IBA	GO_REF
external side of plasma membrane	IEA	GO_REF
ciliary neurotrophic factor receptor complex	ISS	GO_REF
ciliary neurotrophic factor receptor complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

ciliary neurotrophic factor receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

ciliary neurotrophic factor receptor complex

extracellular protein-containing complex [inference]

CNTFR-CLCF1 complex

cellular anatomical structure [inference]

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
ciliary neurotrophic factor receptor activity	ISS	GO_REF
ciliary neurotrophic factor receptor activity	IBA	GO_REF
ciliary neurotrophic factor receptor activity	IEA	GO_REF GO_REF
interleukin-11 receptor activity	IBA	GO_REF
interleukin-11 receptor activity	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

growth factor binding [inference]

interleukin-11 binding

cytokine binding [inference]

interleukin-11 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

immune receptor activity [inference]

cytokine receptor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDLALDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTTHTITDAYAGKEYIIQVAAKDYEIGTWSDWSVAAHATPWTEEPRHLTTEAQAPETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLIHVPVTLALAAAAATANSLLI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
60	N-linked (GlcNAc...) asparagine	UniProt
70	N-linked (GlcNAc...) asparagine	UniProt
142	N-linked (GlcNAc...) asparagine	UniProt
190	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
IL-6-type cytokine receptor ligand interactions	Canis familiaris

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements