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Semaphorin-6D

Summary

UniProt ID: Q76KF0
Gene Symbol: Kiaa1479 Sema6d
Gene ID: 214968
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q76KF0
PubChem: Q76KF0
The O-GlcNAc Database: Q76KF0
O-GlcNAcAtlas: Q76KF0
Re-Glyco: Q76KF0

Annotation

Keyword: Alternative splicing Cell membrane Developmental protein Differentiation Disulfide bond Glycoprotein Neurogenesis Phosphoprotein Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
neural crest cell migration	IBA	GO_REF
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	ISO	GO_REF
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	IDA	PMID
axon guidance	IBA	GO_REF
positive regulation of smooth muscle cell migration	IDA	PMID

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

T cell activation [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

T cell activation [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

signal transduction [inference]

cell surface receptor signaling pathway [inference]

semaphorin-plexin signaling pathway

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

T cell activation [inference]

T cell activation involved in immune response [inference]

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

developmental process [inference]

anatomical structure development [inference]

system development [inference]

ventricular system development

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of developmental growth [inference]

negative regulation of axon extension

regulation of developmental growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of developmental growth [inference]

negative regulation of axon extension

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of smooth muscle cell migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of smooth muscle cell migration [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

negative regulation of cell migration [inference]

negative regulation of smooth muscle cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of smooth muscle cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of smooth muscle cell migration

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of cellular process [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of smooth muscle cell migration

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of developmental growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

semaphorin-plexin signaling pathway

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

negative regulation of cellular process [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of smooth muscle cell migration

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of axonogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of smooth muscle cell migration [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

negative regulation of cell migration [inference]

negative regulation of smooth muscle cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of smooth muscle cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
cytoplasm	ISO	GO_REF
Golgi apparatus	ISO	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 5** entries
GO Term	Evidence Code	Reference
semaphorin receptor binding	IBA	GO_REF
semaphorin receptor binding	IPI	PMID
semaphorin receptor binding	IEA	GO_REF
chemorepellent activity	IBA	GO_REF
receptor ligand activity	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

semaphorin receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

chemorepellent activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

chemorepellent activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGFLLLWFCVLFLLVSRLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPQTEVIPSKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLRTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDDTLAFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIEVDRSAGPYQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNPAKCSAESEEDRKVVSLQLDKDHHALYVAFSSCVVRIPLSRCERYGSCKKSCIASRDPYCGWLSQGVCERVTLGMLPGGYEQDTEYGNTAHLGDCHESLPPSTTPDYKIFGGPTSDMEVSSSSVTTVASSPEITSKVIDTWRPKLTSSRKFVVQDDPNTSDFTDTISGIPKGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNTDTKSMAVDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHSHGASRKEHPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQSMDHPLTKSSSKREHRRSVDSRNTLNDLLKHLNDPNSNPKAILGEIHMAHQTLMLDPVGPMAEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAVPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
51	N-linked (GlcNAc...) asparagine		G14972EH	UniProt GlyGen
283	N-linked (GlcNAc...) asparagine			UniProt GlyGen
435	N-linked (GlcNAc...) asparagine			UniProt GlyGen
461	N-linked (GlcNAc...) asparagine			UniProt GlyGen
631	N-linked (GlcNAc...) asparagine			UniProt GlyGen
1015		22645316 40885482	G49108TO	The O-GlcNAc Database
1018		22645316 40885482	G49108TO	GlyGen The O-GlcNAc Database