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MIRAGE
BRCA1-associated protein
Summary
- UniProt ID
- Q7Z569
- Gene Symbol
-
- BRAP
- RNF52
- Gene ID
- 8315
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Coiled coil
- Cytoplasm
- Phosphoprotein
- Reference proteome
- Transferase
- Ubl conjugation pathway
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| nuclear membrane |
| nucleoplasm |
| cytosol |
| ubiquitin ligase complex |
| GO Term |
|---|
| negative regulation of signal transduction |
| MAPK cascade |
| protein ubiquitination |
| Ras protein signal transduction |
Sequence
MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSKQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKFVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 542 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Negative regulation of MAPK pathway | Homo sapiens |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | Homo sapiens |
| RAF activation | Homo sapiens |
| Signaling by moderate kinase activity BRAF mutants | Homo sapiens |
| Signaling downstream of RAS mutants | Homo sapiens |
