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Pannexin 1

Summary

UniProt ID: Q7ZUN0
Gene Symbol: panx1 panx1a zgc:55631
Gene ID: 393890
Organism: Danio rerio (zebrafish)

External Links

Re-Glyco: Q7ZUN0

Annotation

Keyword: Cell membrane Endoplasmic reticulum Glycoprotein Ion channel Proteomics identification Reference proteome S-nitrosylation Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
monoatomic cation transport	IBA	GO_REF
monoatomic cation transport	IEA	GO_REF
G protein-coupled dopamine receptor signaling pathway	IMP	PMID
cell-cell signaling	IBA	GO_REF
visual perception	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled dopamine receptor signaling pathway

transmembrane transport [inference]

monoatomic ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled dopamine receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of interleukin-1 production

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GO Term	Evidence Code	Reference
endoplasmic reticulum membrane	IEA	GO_REF
plasma membrane	IDA	PMID PMID PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

leading edge membrane [inference]

ruffle membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
channel activity	IDA	PMID
channel activity	IEA	GO_REF
wide pore channel activity	IDA	PMID
wide pore channel activity	IBA	GO_REF
voltage-gated channel activity	IDA	PMID PMID

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

passive transmembrane transporter activity [inference]

channel activity

wide pore channel activity

gap junction hemi-channel activity

gated channel activity [inference]

voltage-gated channel activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAIAHAATEYVFADFVLKDPASENRYKGIRLDLALDKIVTCVAVGLPLLLISLAFAQEVSVGTQISCFAPTAFSWCQAAYVDSYCWAAVQKQDTGGLPLWLHKFFPYILLLVAVSVYMPALFWRFTGAPVLSSDLTFIMEELDRSYNRAIKLAKCLHTAGKVETPPAPVDTNSSVIDLTESYFKYPLVEQYLRTKRYSKGLLIRYLLCRTITVLALTLACIYLCYYISLSTTDEFSCDIRSGVVVNDSSVPPALQCKLVAVGIFQLLSYINLSVYLLLLPLCMFAMLVPFRRTKGFLKPFEMLPTIGVMQFGQATWDDLALYLLFLEENLSELKSYKCLKVLELLKEQGDESFDPMLLLRTLGQVKTDVVDGRLPQKDQKISSTNNGDTELKEFAPLLPEDCLRKHEDEKAVRQRVI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites