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KAT8 regulatory NSL complex subunit 1

Summary

UniProt ID: Q80TG1
Gene Symbol: Kansl1 Kiaa1267 Nsl1
Gene ID: 76719
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q80TG1
PubChem: Q80TG1
The O-GlcNAc Database: Q80TG1
Re-Glyco: Q80TG1

Annotation

Keyword: Acetylation Alternative splicing Centromere Chromatin regulator Chromosome Coiled coil Cytoskeleton Isopeptide bond Kinetochore Microtubule Mitochondrion Nucleus Phosphoprotein Reference proteome Ubl conjugation

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
chromatin organization
positive regulation of transcription, DNA-templated	NAS	PMID
positive regulation of DNA-templated transcription	NAS	PMID
regulation of mitochondrial transcription	ISS	GO_REF
regulation of mitochondrial transcription	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of mitochondrial gene expression [inference]

regulation of mitochondrial transcription

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of mitochondrial gene expression [inference]

regulation of mitochondrial transcription

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	Reference
histone acetyltransferase complex	ISS	GO_REF
histone acetyltransferase complex	ISO	GO_REF
histone acetyltransferase complex	IEA	GO_REF
kinetochore
spindle pole	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

histone methyltransferase complex [inference]

MLL1/2 complex [inference]

MLL1 complex

intracellular protein-containing complex [inference]

protein acetyltransferase complex [inference]

histone acetyltransferase complex

H4 histone acetyltransferase complex [inference]

NSL complex

catalytic complex [inference]

transferase complex [inference]

methyltransferase complex [inference]

histone methyltransferase complex [inference]

MLL1/2 complex [inference]

MLL1 complex

acetyltransferase complex [inference]

protein acetyltransferase complex [inference]

histone acetyltransferase complex

H4 histone acetyltransferase complex [inference]

NSL complex

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular membraneless organelle [inference]

kinetochore

supramolecular complex [inference]

kinetochore

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying 1 entry
GO Term	Evidence Code	Reference
histone acetyltransferase binding	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

histone acetyltransferase binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILISANGTKRKAIAAEDPSLDFRNNPTKEDLGKLQPLVASYLCSDVTSVPAKESLKLQGVFSKQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSSSLNGGKRSLTSSSLQGGEVGGPDSGNLKGGMTNCTLPHRSLDIQHTTLYSNNSTANKSSVNSMDQPALQGSSRLSPSTDSSSNLTNVKLEVKKSPLSSILFSALDSDTRITALLRRQADIEIRARRLQKRLQVVQAKQVERHLQHQLGGFLETTLSKLPNLESLRSRSQLMLTRKAEAALRKAASESATSEGLSNFLKSDSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTRADPEQCHVPLKRRSEWRWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLIVLGEAPFPDHTTDLLSLSSEVKTDHGRDKLIESVSQPSENHGILVSNITESLSTKSCGAPRPVNGVVNSLQPVLADQVPGDSSDAEEQLHKKQRLNLVSSSDGTCVAARTRPVLTCKKRRLVRPSSIVPLSKKVHRNVRSGCDVNPSCALCGSGSVNTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPTKKFSLKHRATMPCSLSDPVRKDRHKLVNSFLTTAMLKHHTDMSSPSYLTATHHPPHSPLVRQLSTSSDTSTPTSSGSQVAASTSQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDVQSLKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLGSANPSTPQPASPDVSSSHSLSEFSHGQSPRSPISPELHSAPLTPVARDSLRHLASEDTRCSTPELGLDEQSVQPWERRTFPLAYSPQAECEEQLDAQDTAARCTRRTSGSKTGREAEVAPTSPPVVPLKSRHLAATVTAQRPAHR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	PubMed ID	GlyTouCan ID	Source
759	36852467 40997131	G49108TO	The O-GlcNAc Database
769	36852467 40997131	G49108TO	The O-GlcNAc Database
1012			GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Formation of WDR5-containing histone-modifying complexes	Mus musculus
HATs acetylate histones	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050880	Koolen de Vries syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements