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Tenascin

Summary

UniProt ID: Q80YX1
Gene Symbol: Tnc Hxb
Gene ID: 21923
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0006112

GlyConnect

Tenascin

GlyGen

Q80YX1

PubChem

Q80YX1

Re-Glyco

Q80YX1

Annotation

Keyword: Alternative splicing Cell adhesion Coiled coil Disulfide bond EGF-like domain Extracellular matrix Phosphoprotein Proteoglycan Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	Reference
regulation of cell growth	ISO	GO_REF
regulation of cell growth	IEA	GO_REF
morphogenesis of an epithelium	IMP	PMID
cell adhesion
negative regulation of cell adhesion	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

mesenchymal-epithelial cell signaling

cell adhesion

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin D

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin D

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

axon development [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

cell junction organization [inference]

synapse organization [inference]

neuromuscular junction development

reproductive process [inference]

developmental process involved in reproduction [inference]

prostate gland epithelium morphogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

prostate gland epithelium morphogenesis

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

odontogenesis [inference]

odontogenesis of dentin-containing tooth

tissue morphogenesis [inference]

morphogenesis of an epithelium

prostate gland epithelium morphogenesis

anatomical structure development [inference]

regeneration [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

growth [inference]

developmental growth [inference]

developmental growth involved in morphogenesis [inference]

axis elongation [inference]

branch elongation of an epithelium [inference]

bud outgrowth involved in lung branching

response to stimulus [inference]

response to stress [inference]

response to wounding

response to axon injury [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

response to external stimulus [inference]

response to mechanical stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

response to growth factor [inference]

response to fibroblast growth factor

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to nutrient levels [inference]

response to nutrient [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin D

response to vitamin [inference]

response to vitamin D [inference]

cellular response to vitamin D

cellular response to vitamin [inference]

cellular response to vitamin D

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin D

response to chemical [inference]

response to nutrient [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin D

response to vitamin [inference]

response to vitamin D [inference]

cellular response to vitamin D

cellular response to vitamin [inference]

cellular response to vitamin D

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

response to lipid [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

response to vitamin D [inference]

cellular response to vitamin D

response to prostaglandin [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin D

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

response to oxygen-containing compound [inference]

response to retinoic acid [inference]

cellular response to retinoic acid

response to vitamin D [inference]

cellular response to vitamin D

response to alcohol [inference]

response to ethanol

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

response to ketone [inference]

response to prostaglandin D [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin D

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

cellular response to chemical stimulus [inference]

cellular response to nutrient [inference]

cellular response to vitamin [inference]

cellular response to vitamin D

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin D stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin D stimulus

cellular response to ketone [inference]

cellular response to prostaglandin D stimulus

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

mesenchymal-epithelial cell signaling

regulation of growth [inference]

regulation of cell growth

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cell adhesion

negative regulation of cell adhesion

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of cell adhesion

regulation of cellular component organization [inference]

regulation of cell growth

regulation of cell motility [inference]

regulation of cell migration

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
extracellular region	TAS	Reactome
extracellular region	IDA	PMID
basement membrane	IDA	PMID PMID PMID
interstitial matrix	IDA	PMID
obsolete extracellular space

GO Hierarchy

cellular component

protein-containing complex [inference]

protein complex involved in cell adhesion [inference]

protein complex involved in cell-matrix adhesion [inference]

tenascin complex

extracellular protein-containing complex [inference]

tenascin complex

cellular anatomical structure [inference]

extracellular region

cell junction [inference]

synapse [inference]

glutamatergic synapse

external encapsulating structure [inference]

extracellular matrix

specialized extracellular matrix [inference]

extracellular matrix of synaptic cleft

synapse-associated extracellular matrix [inference]

perisynaptic extracellular matrix

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GO Term	Evidence Code	Reference
fibronectin binding	ISO	GO_REF
integrin binding	ISS	GO_REF
integrin binding	ISO	GO_REF
integrin binding	IEA	GO_REF
syndecan binding	ISO	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

fibronectin binding

signaling receptor binding [inference]

integrin binding

proteoglycan binding [inference]

syndecan binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

carbohydrate derivative binding [inference]

proteoglycan binding [inference]

syndecan binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGAVTWLLPGIFLALFALTPEGGVLKKIIRHKRESGLNMTLPEENQPVVFNHIYNIKLPMGSQCSVDLESASGEKDLTPTPESSGSFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVKELLSRLEELELLVSSLREQCTMGTGCCLQPAEGRLDTRPFCSGRGNFSAEGCGCVCEPGWKGPNCSEPDCPGNCNLRGQCLDGQCICDEGFTGEDCSQLACPNDCNDQGRCVNGVCVCFEGYAGPDCGLEVCPVPCSEEHGMCVDGRCVCKDGFAGEDCNEPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGELTCPNDCQGRGQCEEGQCVCNEGFAGADCSEKRCPADCHHRGRCLNGQCECDDGFTGADCGDLQCPNGCSGHGRCVNGQCVCDEGYTGEDCSQRRCPNDCHNRGLCVQGKCICEQGFKGFDCSEMSCPNDCHQHGRCVNGMCICDDDYTGEDCRDRRCPRDCSQRGRCVDGQCICEDGFTGPDCAELSCPSDCHGHGRCVNGQCICHEGFTGKDCKEQRCPSDCHGQGRCEDGQCICHEGFTGLDCGQRSCPNDCSNQGQCVSGRCICNEGYTGIDCSEVSPPKDLIVTEVTEETVNLAWDNEMRVTEYLIMYTPTHADGLEMQFRVPGDQTSTTIRELEPGVEYFIRVFAILENKRSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKKVTTTRLDAPSHIEVKDVTDTTALITWFKPLAEIDSIELSYGIKDVPGDRTTIDLTHEDNQYSIGNLRPDTEYEVSLISRRVDMASNPAKETFITGLDAPRNLRRVSQTDNSITLEWRNVKADIDSYRIKYAPISGGDHAEIDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKGDKESDPATINAATEIDAPKDLRVSETTQDSLTFFWTTPLAKFDRYRLNYSLPTGQSMEVQLPKDATSHVLTDLEPGQEYTVLLIAEKGRHKSKPARVKASTEEVPSLENLTVTEAGWDGLRLNWTADDLAYEYFVIQVQEANNVETAHNFTVPGNLRAADIPGLKVATSYRVSIYGVARGYRTPVLSAETSTGTTPNLGEVTVAEVGWDALTLNWTAPEGAYKNFFIQVLEADTTQTVQNLTVPGGLRSVDLPGLKAATRYYITLRGVTQDFGTAPLSVEVLTEDLPQLGGLSVTEVSWDGLTLNWTTDDLAYKHFVVQVQEANNVEAAQNLTVPGSLRAVDIPGLKADTPYRVSIYGVIQGYRTPMLSTDVSTAREPEIGNLNVSDVTPKSFNLSWTATDGIFDMFTIEIIDSNRLLQTAEHNISGAERTAHISGLPPSTDFIVYLSGIAPSIRTKTISTTATTEALPLLENLTISDTNPYGFTVSWTASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVLVSGFTQGHQTKPLRAETITEAEPEVDNLLVSDATPDGFRLSWTADEGIFDSFVIRIRDTKKQSEPQEISLPSPERTRDITGLREATEYEIELYGISRGRRSQPVSAIATTAMGSPKEIMFSDITENAATVSWRAPTAQVESFRITYVPMTGGAPSMVTVDGTDTETRLVKLTPGVEYRVSVIAMKGFEESDPVSGTLITALDGPSGLLIANITDSEALAMWQPAIATVDSYVISYTGERVPEVTRTVSGNTVEYELHDLEPATEYILSIFAEKGQQKSSTIATKFTTDLDSPREFTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYSARIQALSGSLRSKLIQTIFTTIGLLYPFPRDCSQAMLNGDTTSGLYTIYINGDKTQALEVYCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQDHGESAYAVYDRFSVGDAKSRYKLKVEGYSGTAGDSMNYHNGRSFSTYDKDTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSNFRNLEGRRKRA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine		G86182NS	GlycoProtDB UniProt GlyGen
72	O-linked (Xyl...) (chondroitin sulfate) serine			UniProt GlyGen
80				GlyGen
166	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
184	N-linked (GlcNAc...) asparagine		G90039BC	GlycoProtDB UniProt GlyGen
327	N-linked (GlcNAc...) asparagine			UniProt GlyGen
788	N-linked (GlcNAc...) asparagine	30899004	G14972EH G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
1018	N-linked (GlcNAc...) asparagine	30899004	G02815KT G06110VR G66538GV	GlycoProtDB UniProt GlyGen GlyConnect
1079	N-linked (GlcNAc...) asparagine			UniProt GlyGen
1093	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
ECM proteoglycans	Mus musculus
Integrin cell surface interactions	Mus musculus
Post-translational protein phosphorylation	Mus musculus
Regulation of IGF Activity by IGFBP	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements