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Cadherin-5

Summary

UniProt ID: Q8AYD0
Gene Symbol: CDH5
Gene ID: 374068
Organism: Gallus gallus (chicken)

External Links

PubChem: Q8AYD0
Re-Glyco: Q8AYD0

Annotation

Keyword: 3D-structure Calcium Cell adhesion Cell junction Cell membrane Cleavage on pair of basic residues Cytoplasm Glycoprotein Metal-binding Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
cell morphogenesis	IBA	GO_REF
endothelial cell morphogenesis	ISS	GO_REF
cell-cell junction assembly	IBA	GO_REF
homophilic cell-cell adhesion	IEA	GO_REF
calcium-dependent cell-cell adhesion	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition [inference]

cardiac epithelial to mesenchymal transition

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell-cell junction organization [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

epithelial cell morphogenesis [inference]

endothelial cell morphogenesis

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition [inference]

cardiac epithelial to mesenchymal transition

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
cytoplasm	ISS	GO_REF
cytoplasm	IEA	GO_REF
adherens junction	ISS	GO_REF
adherens junction	IBA	GO_REF
adherens junction	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical structure [inference]

cytoplasm

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

tight junction [inference]

bicellular tight junction

Displaying **all 4** entries
GO Term	Evidence Code	Reference
calcium ion binding	IEA	GO_REF
beta-catenin binding	IBA	GO_REF
protein phosphatase binding	IBA	GO_REF
cadherin binding	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

cell adhesion molecule binding [inference]

cadherin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKKLILLFSLFLAPAFSYKENQKINQNFSSNNTSHKRLKRDWIWNRMHIREEIDSPLPHHVGKLTSSVGNKNAMYIIEGESANTIFKVQGYDGDIYAFERLDREKKAEYELTAHIIDRRNNRSLEPPSKFIIKVSDINDNAPIFVQKIFNGSVPEMSRLGTSVTKVTAEDADDPTVAGHATVTYQIIKGNEYFTVDDSGVISTARADLDRESQSAYEIIVKAKDALGLTGESSTATVIIRLTDINDNFPVFKHPSFHFRVPENISVGGEVGRVKVEDIDEPQHRNTKYSFVRGDYRDTFEIIANPFTNEGIIRPKKPLDFEKVAEYRFDIEATDHNVNPAYYKPGGSRSISTITIEVTDVDEPPVFTKLSYEFKVRENDPEIKTLGSVWAHDPDAAKRKIRFARRRASPNGDYVRVSDSGIIQLPKPLDREFSSLYNITVAAQEILEDGRLSDRESHAQVHVIVTDENDNAPELVYPEEPRVCENAAPGKVIIRISATDKDEISPGGFFTYSLTTEDSNFSLTENPDNTANITVKDGQFNRELAKIHYLPVIISDNGNPELSSTNTLVISVCKCNEKGDFTFCEERAKQVGVSVQALVAIFICIFTIIAVIALLILLRKRHKKDLSGLRRNVAEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRKNGIKPEVVPSAYAQVQKPPGNTTSGAGEMEMMIEVKKDEADNDRDLLPYDTLHIYGYEGAESIAESLSSLESGSSDSDIDYDFLNDWGPRFKMLAELYGSEPNEDFVY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	Source
27	N-linked (GlcNAc...) asparagine	UniProt
31	N-linked (GlcNAc...) asparagine	UniProt
32	N-linked (GlcNAc...) asparagine	UniProt
121	N-linked (GlcNAc...) asparagine	UniProt
150	N-linked (GlcNAc...) asparagine	UniProt
263	N-linked (GlcNAc...) asparagine	UniProt
437	N-linked (GlcNAc...) asparagine	UniProt
519	N-linked (GlcNAc...) asparagine	UniProt
531	N-linked (GlcNAc...) asparagine	UniProt