GlyCosmos Portal

Submissions

5'-3' exonuclease PLD4

Summary

UniProt ID: Q8BG07
Gene Symbol: Pld4
Gene ID: 104759
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0006167

GlyConnect

Phospholipase D4

GlyGen

Q8BG07

PubChem

Q8BG07

Re-Glyco

Q8BG07

Annotation

Keyword: Alternative splicing Cytoplasmic vesicle Disulfide bond Endoplasmic reticulum Endosome Exonuclease Glycoprotein Golgi apparatus Inflammatory response Innate immunity Lysosome Nucleus Phospholipid metabolism Reference proteome Repeat Signal-anchor Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
hematopoietic progenitor cell differentiation	IMP	PMID
lipid metabolic process
phagocytosis	IMP	PMID
phagocytosis	IBA	GO_REF
inflammatory response

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

import into cell [inference]

endocytosis [inference]

phagocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

Displaying entries **1 - 5** of 15 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	Reference
nucleus	IDA	PMID
nucleus	IEA	GO_REF
lysosome	ISS	GO_REF
lysosome	ISO	GO_REF
lysosome	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

endomembrane system

membrane [inference]

organelle membrane [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

endocytic vesicle [inference]

phagocytic vesicle

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

endocytic vesicle [inference]

phagocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

endocytic vesicle [inference]

phagocytic vesicle

Displaying **all 3** entries
GO Term	Evidence Code	Reference
D-type glycerophospholipase activity	TAS	Reactome
D-type glycerophospholipase activity	IDA	PMID
single-stranded DNA 5'-3' DNA exonuclease activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' exonuclease activity [inference]

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

lipase activity [inference]

phospholipase activity [inference]

glycerophospholipase activity [inference]

D-type glycerophospholipase activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

D-type glycerophospholipase activity

catalytic activity, acting on a nucleic acid [inference]

nuclease activity [inference]

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' exonuclease activity [inference]

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

DNA nuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDKKKEHPEMRIPLQTAVEVSDWPCSTSHDPHSGLGMVLGMLAVLGLSSVTLILFLWQGATSFTSHRMFPEEVPSWSWETLKGDAEQQNNSCQLILVESIPEDLPFAAGSPTAQPLAQAWLQLLDTARESVHIASYYWSLTGLDIGVNDSSSRQGEALLQKFQQLLLRNISVVVATHSPTLAKTSTDLQVLAAHGAQIRQVPMKQLTGGVLHSKFWVVDGRHIYVGSANMDWRSLTQVKELGAIIYNCSNLAQDLEKTFQTYWVLGTPQAVLPKTWPRNFSSHINRFHPLRGPFDGVPTTAYFSASPPSLCPHGRTRDLDAVLGVMEGARQFIYVSVMEYFPTTRFTHHARYWPVLDNALRAAALNKGVHVRLLVSCWFNTDPTMFAYLRSLQAFSNPSAGISVDVKVFIVPVGNHSNIPFSRVNHSKFMVTDKTAYVGTSNWSEDYFSHTAGVGLIVSQKTPRAQPGATTVQEQLRQLFERDWSSHYAMDLDRQVPSQDCVW

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
89	N-linked (GlcNAc...) asparagine			UniProt GlyGen
148	N-linked (GlcNAc...) asparagine		G28603RA	UniProt GlyGen
169	N-linked (GlcNAc...) asparagine	30899004	G80920RR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
247	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
279	N-linked (GlcNAc...) asparagine	30899004	G23294PN G80920RR G06110VR G66538GV	GlycoProtDB UniProt GlyGen GlyConnect
415	N-linked (GlcNAc...) asparagine	30899004	G80920RR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
425	N-linked (GlcNAc...) asparagine			UniProt GlyGen
442	N-linked (GlcNAc...) asparagine			UniProt GlyGen