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Serine incorporator 5

Summary

UniProt ID: Q8BHJ6
Gene Symbol: Serinc5 Aigp3
Gene ID: 218442
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0006205
PubChem: Q8BHJ6
Re-Glyco: Q8BHJ6

Annotation

Keyword: Antiviral defense Cell membrane Glycoprotein Innate immunity Phospholipid biosynthesis Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
phosphatidylserine metabolic process	ISS	GO_REF
phosphatidylserine metabolic process	ISO	GO_REF
phospholipid biosynthetic process
plasma membrane phospholipid scrambling	ISS	GO_REF
plasma membrane phospholipid scrambling	ISO	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response [inference]

antiviral innate immune response

cellular process [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

metabolic process [inference]

modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

phospholipid biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane phospholipid scrambling

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

antiviral innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

antiviral innate immune response

immune response [inference]

innate immune response [inference]

antiviral innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

antiviral innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

antiviral innate immune response

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

organophosphate ester transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
Golgi apparatus	IDA	PMID
centrosome	ISO	GO_REF
cytosol	ISO	GO_REF
cytosol	IEA	GO_REF
plasma membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

microtubule organizing center [inference]

centrosome

cytosol

membrane

plasma membrane

myelin sheath

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 5** entries
GO Term	Evidence Code	Reference
acetyltransferase activator activity	ISS	GO_REF
acetyltransferase activator activity	ISO	GO_REF
phospholipid scramblase activity	ISS	GO_REF
phospholipid scramblase activity	ISO	GO_REF
phospholipid scramblase activity	IEA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

intramembrane lipid carrier activity [inference]

phospholipid scramblase activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

acetyltransferase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

acetyltransferase activator activity

molecular carrier activity [inference]

lipid carrier activity [inference]

intramembrane lipid carrier activity [inference]

phospholipid scramblase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSARCCAGQLACCCGSAGCSLCCGCCPKFRQSRTTRFMYLFYFILVIALCCVMMTPSVMKQVKDHIPFFEEFCKKTQAGGDACENLVGYSAVYRVCFGMACFFALFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLKVWRYVGAGGSFLFICIQLLLIVQFAHKWNKNWTAGTVRNKLWYASLSLVTLIMYSVAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLVAISPCVQNRQPHSGLLQSGLISCYVTYLTFSALTSKPEKKVLDEHGKNVTICAPDFGQDLHRDENMVTWLGTLLLIVCISYSCLTSTTRSSSDALQSRYGAPELEVARCCFCFGPDGEDTEEQQNVKKGPRVIYDEKKGTVYSYSYFHFVFFLASLYVMMTLTSWFHYENATIKTFFSGWSVFWVKMASCWMCVLLYLQTLVAPLCCPSRQFSV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
114	N-linked (GlcNAc...) asparagine	UniProt
184	N-linked (GlcNAc...) asparagine	UniProt
295		GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Serine metabolism	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements